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Increased transport of acetyl-CoA into the endoplasmic reticulum causes a progeria-like phenotype.
Peng Y, Shapiro SL, Banduseela VC, Dieterich IA, Hewitt KJ, Bresnick EH, Kong G, Zhang J, Schueler KL, Keller MP, Attie AD, Hacker TA, Sullivan R, Kielar-Grevstad E, Arriola Apelo SI, Lamming DW, Anderson RM, Puglielli L. Peng Y, et al. Among authors: kielar grevstad e. Aging Cell. 2018 Oct;17(5):e12820. doi: 10.1111/acel.12820. Epub 2018 Jul 27. Aging Cell. 2018. PMID: 30051577 Free PMC article.