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A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.
Conway E, Jerman E, Healy E, Ito S, Holoch D, Oliviero G, Deevy O, Glancy E, Fitzpatrick DJ, Mucha M, Watson A, Rice AM, Chammas P, Huang C, Pratt-Kelly I, Koseki Y, Nakayama M, Ishikura T, Streubel G, Wynne K, Hokamp K, McLysaght A, Ciferri C, Di Croce L, Cagney G, Margueron R, Koseki H, Bracken AP. Conway E, et al. Among authors: healy e. Mol Cell. 2018 May 3;70(3):408-421.e8. doi: 10.1016/j.molcel.2018.03.005. Epub 2018 Apr 5. Mol Cell. 2018. PMID: 29628311 Free article.
PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation.
Healy E, Mucha M, Glancy E, Fitzpatrick DJ, Conway E, Neikes HK, Monger C, Van Mierlo G, Baltissen MP, Koseki Y, Vermeulen M, Koseki H, Bracken AP. Healy E, et al. Mol Cell. 2019 Nov 7;76(3):437-452.e6. doi: 10.1016/j.molcel.2019.08.012. Epub 2019 Sep 11. Mol Cell. 2019. PMID: 31521505 Free article.
Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells.
Brien GL, Bressan RB, Monger C, Gannon D, Lagan E, Doherty AM, Healy E, Neikes H, Fitzpatrick DJ, Deevy O, Grant V, Marqués-Torrejón MA, Alfazema N, Pollard SM, Bracken AP. Brien GL, et al. Among authors: healy e. Nat Genet. 2021 Aug;53(8):1221-1232. doi: 10.1038/s41588-021-00897-w. Epub 2021 Jul 22. Nat Genet. 2021. PMID: 34294917
A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence.
Brien GL, Healy E, Jerman E, Conway E, Fadda E, O'Donovan D, Krivtsov AV, Rice AM, Kearney CJ, Flaus A, McDade SS, Martin SJ, McLysaght A, O'Connell DJ, Armstrong SA, Bracken AP. Brien GL, et al. Among authors: healy e. Genes Dev. 2015 Nov 1;29(21):2231-43. doi: 10.1101/gad.267930.115. Epub 2015 Oct 22. Genes Dev. 2015. PMID: 26494712 Free PMC article.
391 results