Tseng JL - Search Results

1

Reversible, orally available ADP receptor (P2Y₁₂) antagonists Part I: Hit to lead process.

Islam I, Yuan S, Wei RG, Xu W, Morrissey M, Mohan R, Zheng D, DiMella A, Dunning L, Snider M, Subramanyam B, Tseng JL, Bryant JA, Buckman BO. Islam I, et al. Among authors: tseng jl. Bioorg Med Chem Lett. 2018 May 15;28(9):1459-1463. doi: 10.1016/j.bmcl.2018.03.090. Epub 2018 Mar 31. Bioorg Med Chem Lett. 2018. PMID: 29628327

2

CCR5 receptor antagonists: discovery and SAR of novel 4-hydroxypiperidine derivatives.

Lu SF, Chen B, Davey D, Dunning L, Jaroch S, May K, Onuffer J, Phillips G, Subramanyam B, Tseng JL, Wei RG, Wei M, Ye B. Lu SF, et al. Among authors: tseng jl. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1883-7. doi: 10.1016/j.bmcl.2007.01.050. Epub 2007 Jan 25. Bioorg Med Chem Lett. 2007. PMID: 17314043

3

Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (I): in vitro effects on platelets.

Bryant J, Post JM, Alexander S, Wang YX, Kent L, Schirm S, Tseng JL, Subramanyam B, Buckman B, Islam I, Yuan S, Sullivan ME, Snider M, Morser J. Bryant J, et al. Among authors: tseng jl. Thromb Res. 2008;122(4):523-32. doi: 10.1016/j.thromres.2008.03.026. Epub 2008 May 20. Thromb Res. 2008. PMID: 18495218

4

1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formation.

Wei RG, Adler M, Davey D, Ho E, Mohan R, Polokoff M, Tseng JL, Whitlow M, Xu W, Yuan S, Phillips G. Wei RG, et al. Among authors: tseng jl. Bioorg Med Chem Lett. 2007 May 1;17(9):2499-504. doi: 10.1016/j.bmcl.2007.02.053. Epub 2007 Feb 27. Bioorg Med Chem Lett. 2007. PMID: 17368901

5

Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase.

Ye B, Bauman J, Chen M, Davey D, Khim SK, King B, Kirkland T, Kochanny M, Liang A, Lentz D, May K, Mendoza L, Phillips G, Selchau V, Schlyer S, Tseng JL, Wei RG, Ye H, Parkinson J, Guilford WJ. Ye B, et al. Among authors: tseng jl. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3891-4. doi: 10.1016/j.bmcl.2008.06.046. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18586492

6

Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.

Khim SK, Bauman J, Evans J, Freeman B, King B, Kirkland T, Kochanny M, Lentz D, Liang A, Mendoza L, Phillips G, Tseng JL, Wei RG, Ye H, Yu L, Parkinson J, Guilford WJ. Khim SK, et al. Among authors: tseng jl. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3895-8. doi: 10.1016/j.bmcl.2008.06.041. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18590959

7

Novel 3-oxa lipoxin A4 analogues with enhanced chemical and metabolic stability have anti-inflammatory activity in vivo.

Guilford WJ, Bauman JG, Skuballa W, Bauer S, Wei GP, Davey D, Schaefer C, Mallari C, Terkelsen J, Tseng JL, Shen J, Subramanyam B, Schottelius AJ, Parkinson JF. Guilford WJ, et al. Among authors: tseng jl. J Med Chem. 2004 Apr 8;47(8):2157-65. doi: 10.1021/jm030569l. J Med Chem. 2004. PMID: 15056011

8

Measurements of drug-protein binding by using immobilized human serum albumin liquid chromatography-mass spectrometry.

Cheng Y, Ho E, Subramanyam B, Tseng JL. Cheng Y, et al. Among authors: tseng jl. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Sep 25;809(1):67-73. doi: 10.1016/j.jchromb.2004.06.006. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15282095

9

Potent triazolothione inhibitor of heat-shock protein-90.

Feldman RI, Mintzer B, Zhu D, Wu JM, Biroc SL, Yuan S, Emayan K, Chang Z, Chen D, Arnaiz DO, Bryant J, Ge XS, Whitlow M, Adler M, Polokoff MA, Li WW, Ferrer M, Sato T, Gu JM, Shen J, Tseng JL, Dinter H, Buckman B. Feldman RI, et al. Among authors: tseng jl. Chem Biol Drug Des. 2009 Jul;74(1):43-50. doi: 10.1111/j.1747-0285.2009.00833.x. Chem Biol Drug Des. 2009. PMID: 19519743

10

Synthesis and biological evaluation of piperazine-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1).

Ye B, Chou YL, Karanjawala R, Lee W, Lu SF, Shaw KJ, Jones S, Lentz D, Liang A, Tseng JL, Wu Q, Zhao Z. Ye B, et al. Among authors: tseng jl. Bioorg Med Chem Lett. 2004 Feb 9;14(3):761-5. doi: 10.1016/j.bmcl.2003.11.035. Bioorg Med Chem Lett. 2004. PMID: 14741285

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