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Page 1
Reversible, orally available ADP receptor (P2Y12) antagonists Part I: Hit to lead process.
Islam I, Yuan S, Wei RG, Xu W, Morrissey M, Mohan R, Zheng D, DiMella A, Dunning L, Snider M, Subramanyam B, Tseng JL, Bryant JA, Buckman BO. Islam I, et al. Among authors: wei rg. Bioorg Med Chem Lett. 2018 May 15;28(9):1459-1463. doi: 10.1016/j.bmcl.2018.03.090. Epub 2018 Mar 31. Bioorg Med Chem Lett. 2018. PMID: 29628327
Design, synthesis, and activity of 2-imidazol-1-ylpyrimidine derived inducible nitric oxide synthase dimerization inhibitors.
Davey DD, Adler M, Arnaiz D, Eagen K, Erickson S, Guilford W, Kenrick M, Morrissey MM, Ohlmeyer M, Pan G, Paradkar VM, Parkinson J, Polokoff M, Saionz K, Santos C, Subramanyam B, Vergona R, Wei RG, Whitlow M, Ye B, Zhao ZS, Devlin JJ, Phillips G. Davey DD, et al. Among authors: wei rg. J Med Chem. 2007 Mar 22;50(6):1146-57. doi: 10.1021/jm061319i. Epub 2007 Feb 23. J Med Chem. 2007. PMID: 17315988
Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase.
Ye B, Bauman J, Chen M, Davey D, Khim SK, King B, Kirkland T, Kochanny M, Liang A, Lentz D, May K, Mendoza L, Phillips G, Selchau V, Schlyer S, Tseng JL, Wei RG, Ye H, Parkinson J, Guilford WJ. Ye B, et al. Among authors: wei rg. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3891-4. doi: 10.1016/j.bmcl.2008.06.046. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18586492
Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.
Khim SK, Bauman J, Evans J, Freeman B, King B, Kirkland T, Kochanny M, Lentz D, Liang A, Mendoza L, Phillips G, Tseng JL, Wei RG, Ye H, Yu L, Parkinson J, Guilford WJ. Khim SK, et al. Among authors: wei rg. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3895-8. doi: 10.1016/j.bmcl.2008.06.041. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18590959
13 results