Xu J - Search Results

1

Pharmacological Characterization of Levorphanol, a G-Protein Biased Opioid Analgesic.

Le Rouzic V, Narayan A, Hunkle A, Marrone GF, Lu Z, Majumdar S, Xu J, Pan YX, Pasternak GW. Le Rouzic V, et al. Among authors: xu j. Anesth Analg. 2019 Feb;128(2):365-373. doi: 10.1213/ANE.0000000000003360. Anesth Analg. 2019. PMID: 29649035 Free PMC article.

2

Identification and characterization of seven new exon 11-associated splice variants of the rat μ opioid receptor gene, OPRM1.

Xu J, Xu M, Rossi GC, Pasternak GW, Pan YX. Xu J, et al. Among authors: xu m. Mol Pain. 2011 Jan 21;7:9. doi: 10.1186/1744-8069-7-9. Mol Pain. 2011. PMID: 21255438 Free PMC article.

3

Morphine regulates expression of μ-opioid receptor MOR-1A, an intron-retention carboxyl terminal splice variant of the μ-opioid receptor (OPRM1) gene via miR-103/miR-107.

Lu Z, Xu J, Xu M, Pasternak GW, Pan YX. Lu Z, et al. Among authors: xu m, xu j. Mol Pharmacol. 2014 Feb;85(2):368-80. doi: 10.1124/mol.113.089292. Epub 2013 Dec 3. Mol Pharmacol. 2014. PMID: 24302561 Free PMC article.

4

Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P.

Xu J, Xu M, Bolan E, Gilbert AK, Pasternak GW, Pan YX. Xu J, et al. Among authors: xu m. Synapse. 2014 Apr;68(4):144-52. doi: 10.1002/syn.21727. Epub 2014 Jan 16. Synapse. 2014. PMID: 24375714 Free PMC article.

5

Stabilization of morphine tolerance with long-term dosing: association with selective upregulation of mu-opioid receptor splice variant mRNAs.

Xu J, Faskowitz AJ, Rossi GC, Xu M, Lu Z, Pan YX, Pasternak GW. Xu J, et al. Among authors: xu m. Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):279-84. doi: 10.1073/pnas.1419183112. Epub 2014 Dec 22. Proc Natl Acad Sci U S A. 2015. PMID: 25535370 Free PMC article.

6

Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS.

Marrone GF, Grinnell SG, Lu Z, Rossi GC, Le Rouzic V, Xu J, Majumdar S, Pan YX, Pasternak GW. Marrone GF, et al. Among authors: xu j. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3663-8. doi: 10.1073/pnas.1523894113. Epub 2016 Mar 14. Proc Natl Acad Sci U S A. 2016. PMID: 26976581 Free PMC article.

7

Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants.

Grinnell SG, Ansonoff M, Marrone GF, Lu Z, Narayan A, Xu J, Rossi G, Majumdar S, Pan YX, Bassoni DL, Pintar J, Pasternak GW. Grinnell SG, et al. Among authors: xu j. Synapse. 2016 Oct;70(10):395-407. doi: 10.1002/syn.21914. Epub 2016 Jul 12. Synapse. 2016. PMID: 27223691 Free PMC article.

8

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2.

Váradi A, Marrone GF, Palmer TC, Narayan A, Szabó MR, Le Rouzic V, Grinnell SG, Subrath JJ, Warner E, Kalra S, Hunkele A, Pagirsky J, Eans SO, Medina JM, Xu J, Pan YX, Borics A, Pasternak GW, McLaughlin JP, Majumdar S. Váradi A, et al. Among authors: xu j. J Med Chem. 2016 Sep 22;59(18):8381-97. doi: 10.1021/acs.jmedchem.6b00748. Epub 2016 Sep 2. J Med Chem. 2016. PMID: 27556704 Free PMC article.

9

Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for Analgesia.

Marrone GF, Lu Z, Rossi G, Narayan A, Hunkele A, Marx S, Xu J, Pintar J, Majumdar S, Pan YX, Pasternak GW. Marrone GF, et al. Among authors: xu j. ACS Chem Neurosci. 2016 Dec 21;7(12):1717-1727. doi: 10.1021/acschemneuro.6b00240. Epub 2016 Oct 10. ACS Chem Neurosci. 2016. PMID: 27648914 Free PMC article.

10

Genetic dissociation of morphine analgesia from hyperalgesia in mice.

Marrone GF, Le Rouzic V, Varadi A, Xu J, Rajadhyaksha AM, Majumdar S, Pan YX, Pasternak GW. Marrone GF, et al. Among authors: xu j. Psychopharmacology (Berl). 2017 Jun;234(12):1891-1900. doi: 10.1007/s00213-017-4600-2. Epub 2017 Mar 25. Psychopharmacology (Berl). 2017. PMID: 28343361 Free PMC article.

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