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Page 1
Discovery of a Potent and Orally Efficacious TGR5 Receptor Agonist.
Agarwal S, Patil A, Aware U, Deshmukh P, Darji B, Sasane S, Sairam KV, Priyadarsiny P, Giri P, Patel H, Giri S, Jain M, Desai RC. Agarwal S, et al. Among authors: giri p, giri s. ACS Med Chem Lett. 2015 Nov 20;7(1):51-5. doi: 10.1021/acsmedchemlett.5b00323. eCollection 2016 Jan 14. ACS Med Chem Lett. 2015. PMID: 26819665 Free PMC article.
Identification of an Orally Efficacious GPR40/FFAR1 Receptor Agonist.
Agarwal S, Sasane S, Deshmukh P, Rami B, Bandyopadhyay D, Giri P, Giri S, Jain M, Desai RC. Agarwal S, et al. Among authors: giri p, giri s. ACS Med Chem Lett. 2016 Sep 21;7(12):1134-1138. doi: 10.1021/acsmedchemlett.6b00331. eCollection 2016 Dec 8. ACS Med Chem Lett. 2016. PMID: 27994752 Free PMC article.
Identification and preclinical characterization of a novel and potent poly (ADP-ribose) polymerase (PARP) inhibitor ZYTP1.
Jain MR, Mohapatra J, Bandhyopadhyay D, Chatterjee A, Ghoshdastidar K, Patel D, Patel A, Bhayani H, Srivastava BK, Shedage SA, Kadam P, Sundar R, Patel H, Giri P, Patel P, Gupta L, Srinivas NR, Patel PR, Desai RC. Jain MR, et al. Among authors: giri p. Cancer Chemother Pharmacol. 2018 Oct;82(4):635-647. doi: 10.1007/s00280-018-3653-1. Epub 2018 Jul 25. Cancer Chemother Pharmacol. 2018. PMID: 30046848
Lack of inhibition of CYP2C8 by saroglitazar magnesium: In vivo assessment using montelukast, rosiglitazone, pioglitazone, repaglinide and paclitaxel as victim drugs in Wistar rats.
Giri P, Delvadia P, Ladani MK, Prajapati N, Gupta L, Patel N, Joshi V, Giri S, Jain MR, Srinivas NR, Patel PR. Giri P, et al. Among authors: giri s. Eur J Pharm Sci. 2019 Mar 15;130:107-113. doi: 10.1016/j.ejps.2019.01.005. Epub 2019 Jan 8. Eur J Pharm Sci. 2019. PMID: 30633968
Discovery of 1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-ones based novel, potent and PI3Kδ selective inhibitors.
Bahekar R, Dave B, Soman S, Patel D, Chopade R, Funde R, Kumar J, Sachchidanand S, Giri P, Chatterjee A, Mahapatra J, Vyas P, Ghoshdastidar K, Bandyopadhyay D, Desai RC. Bahekar R, et al. Among authors: giri p. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1313-1319. doi: 10.1016/j.bmcl.2019.04.007. Epub 2019 Apr 4. Bioorg Med Chem Lett. 2019. PMID: 30975623
Discovery of N-Cyano-sulfoximineurea Derivatives as Potent and Orally Bioavailable NLRP3 Inflammasome Inhibitors.
Agarwal S, Sasane S, Shah HA, Pethani JP, Deshmukh P, Vyas V, Iyer P, Bhavsar H, Viswanathan K, Bandyopadhyay D, Giri P, Mahapatra J, Chatterjee A, Jain MR, Sharma R. Agarwal S, et al. Among authors: giri p. ACS Med Chem Lett. 2020 Feb 27;11(4):414-418. doi: 10.1021/acsmedchemlett.9b00433. eCollection 2020 Apr 9. ACS Med Chem Lett. 2020. PMID: 32292543 Free PMC article.
ZYBT1, a potent, irreversible Bruton's Tyrosine Kinase (BTK) inhibitor that inhibits the C481S BTK with profound efficacy against arthritis and cancer.
Ghoshdastidar K, Patel H, Bhayani H, Patel A, Thakkar K, Patel D, Sharma M, Singh J, Mohapatra J, Chatterjee A, Patel D, Bahekar R, Sharma R, Gupta L, Patel N, Giri P, Srinivas NR, Jain M, Bandyopadhyay D, Patel PR, Desai RC. Ghoshdastidar K, et al. Among authors: giri p. Pharmacol Res Perspect. 2020 Aug;8(4):e00565. doi: 10.1002/prp2.565. Pharmacol Res Perspect. 2020. PMID: 32790160 Free PMC article.
456 results