Towers CG - Search Results

1

The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L.

Guarnieri AL, Towers CG, Drasin DJ, Oliphant MUJ, Andrysik Z, Hotz TJ, Vartuli RL, Linklater ES, Pandey A, Khanal S, Espinosa JM, Ford HL. Guarnieri AL, et al. Among authors: towers cg. Oncogene. 2018 Jul;37(28):3879-3893. doi: 10.1038/s41388-018-0239-7. Epub 2018 Apr 17. Oncogene. 2018. PMID: 29662198 Free PMC article.

2

The SIX1-EYA transcriptional complex as a therapeutic target in cancer.

Blevins MA, Towers CG, Patrick AN, Zhao R, Ford HL. Blevins MA, et al. Among authors: towers cg. Expert Opin Ther Targets. 2015 Feb;19(2):213-25. doi: 10.1517/14728222.2014.978860. Epub 2015 Jan 2. Expert Opin Ther Targets. 2015. PMID: 25555392 Free PMC article. Review.

3

The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.

Towers CG, Guarnieri AL, Micalizzi DS, Harrell JC, Gillen AE, Kim J, Wang CA, Oliphant MUJ, Drasin DJ, Guney MA, Kabos P, Sartorius CA, Tan AC, Perou CM, Espinosa JM, Ford HL. Towers CG, et al. Nat Commun. 2015 Dec 21;6:10077. doi: 10.1038/ncomms10077. Nat Commun. 2015. PMID: 26687066 Free PMC article.

4

A tale of two ends.

Towers CG, Ford HL. Towers CG, et al. Cell Cycle. 2016 Jun 17;15(12):1523-4. doi: 10.1080/15384101.2016.1171652. Epub 2016 Apr 21. Cell Cycle. 2016. PMID: 27101085 Free PMC article. No abstract available.

5

A Genome-Wide Loss-of-Function Screen Identifies SLC26A2 as a Novel Mediator of TRAIL Resistance.

Dimberg LY, Towers CG, Behbakht K, Hotz TJ, Kim J, Fosmire S, Porter CC, Tan AC, Thorburn A, Ford HL. Dimberg LY, et al. Among authors: towers cg. Mol Cancer Res. 2017 Apr;15(4):382-394. doi: 10.1158/1541-7786.MCR-16-0234. Epub 2017 Jan 20. Mol Cancer Res. 2017. PMID: 28108622 Free PMC article.

6

Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover.

Fitzwalter BE, Towers CG, Sullivan KD, Andrysik Z, Hoh M, Ludwig M, O'Prey J, Ryan KM, Espinosa JM, Morgan MJ, Thorburn A. Fitzwalter BE, et al. Among authors: towers cg. Dev Cell. 2018 Mar 12;44(5):555-565.e3. doi: 10.1016/j.devcel.2018.02.014. Dev Cell. 2018. PMID: 29533771 Free PMC article.

7

Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition.

Towers CG, Fitzwalter BE, Regan D, Goodspeed A, Morgan MJ, Liu CW, Gustafson DL, Thorburn A. Towers CG, et al. Dev Cell. 2019 Sep 23;50(6):690-703.e6. doi: 10.1016/j.devcel.2019.07.010. Epub 2019 Aug 1. Dev Cell. 2019. PMID: 31378590 Free PMC article.

8

Circumventing autophagy inhibition.

Towers CG, Thorburn A. Towers CG, et al. Cell Cycle. 2019 Dec;18(24):3421-3431. doi: 10.1080/15384101.2019.1692483. Epub 2019 Nov 18. Cell Cycle. 2019. PMID: 31736401 Free PMC article. Review.

9

Autophagy and cancer: Modulation of cell death pathways and cancer cell adaptations.

Towers CG, Wodetzki D, Thorburn A. Towers CG, et al. J Cell Biol. 2020 Jan 6;219(1):e201909033. doi: 10.1083/jcb.201909033. J Cell Biol. 2020. PMID: 31753861 Free PMC article. Review.

10

Targeting the Lysosome for Cancer Therapy.

Towers CG, Thorburn A. Towers CG, et al. Cancer Discov. 2017 Nov;7(11):1218-1220. doi: 10.1158/2159-8290.CD-17-0996. Cancer Discov. 2017. PMID: 29097619 Free PMC article.

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