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Page 1
A role for noncoding variation in schizophrenia.
Roussos P, Mitchell AC, Voloudakis G, Fullard JF, Pothula VM, Tsang J, Stahl EA, Georgakopoulos A, Ruderfer DM, Charney A, Okada Y, Siminovitch KA, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Plenge RM, Raychaudhuri S, Fromer M, Purcell SM, Brennand KJ, Robakis NK, Schadt EE, Akbarian S, Sklar P. Roussos P, et al. Among authors: akbarian s. Cell Rep. 2014 Nov 20;9(4):1417-29. doi: 10.1016/j.celrep.2014.10.015. Epub 2014 Nov 6. Cell Rep. 2014. PMID: 25453756 Free PMC article.
Spatial genome organization and cognition.
Rajarajan P, Gil SE, Brennand KJ, Akbarian S. Rajarajan P, et al. Among authors: akbarian s. Nat Rev Neurosci. 2016 Nov;17(11):681-691. doi: 10.1038/nrn.2016.124. Epub 2016 Oct 6. Nat Rev Neurosci. 2016. PMID: 27708356 Free PMC article. Review.
MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice.
Mitchell AC, Javidfar B, Pothula V, Ibi D, Shen EY, Peter CJ, Bicks LK, Fehr T, Jiang Y, Brennand KJ, Neve RL, Gonzalez-Maeso J, Akbarian S. Mitchell AC, et al. Among authors: akbarian s. Mol Psychiatry. 2018 Jan;23(1):123-132. doi: 10.1038/mp.2016.254. Epub 2017 Jan 24. Mol Psychiatry. 2018. PMID: 28115742 Free PMC article.
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain.
Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, Peter CJ, C W JT, Safaie BM, Morishita H, Roussos P, Nestler EJ, Schaefer A, Tycko B, Brennand KJ, Yagi T, Shen L, Akbarian S. Jiang Y, et al. Among authors: akbarian s. Nat Genet. 2017 Aug;49(8):1239-1250. doi: 10.1038/ng.3906. Epub 2017 Jul 3. Nat Genet. 2017. PMID: 28671686 Free PMC article.
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk.
Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casiño C, Powell S, Yashaswini C, LaMarca EA, Kassim B, Javidfar B, Espeso-Gil S, Li A, Won H, Geschwind DH, Ho SM, MacDonald M, Hoffman GE, Roussos P, Zhang B, Hahn CG, Weng Z, Brennand KJ, Akbarian S. Rajarajan P, et al. Among authors: akbarian s. Science. 2018 Dec 14;362(6420):eaat4311. doi: 10.1126/science.aat4311. Science. 2018. PMID: 30545851 Free PMC article.
Spatial genome exploration in the context of cognitive and neurological disease.
Rajarajan P, Borrman T, Liao W, Espeso-Gil S, Chandrasekaran S, Jiang Y, Weng Z, Brennand KJ, Akbarian S. Rajarajan P, et al. Among authors: akbarian s. Curr Opin Neurobiol. 2019 Dec;59:112-119. doi: 10.1016/j.conb.2019.05.007. Epub 2019 Jun 27. Curr Opin Neurobiol. 2019. PMID: 31255842 Free PMC article. Review.
CRISPR-based functional evaluation of schizophrenia risk variants.
Rajarajan P, Flaherty E, Akbarian S, Brennand KJ. Rajarajan P, et al. Among authors: akbarian s. Schizophr Res. 2020 Mar;217:26-36. doi: 10.1016/j.schres.2019.06.017. Epub 2019 Jul 3. Schizophr Res. 2020. PMID: 31277978 Free PMC article.
287 results