Wang Z - Search Results

1

The Heteroaryldihydropyrimidine Bay 38-7690 Induces Hepatitis B Virus Core Protein Aggregates Associated with Promyelocytic Leukemia Nuclear Bodies in Infected Cells.

Huber AD, Wolf JJ, Liu D, Gres AT, Tang J, Boschert KN, Puray-Chavez MN, Pineda DL, Laughlin TG, Coonrod EM, Yang Q, Ji J, Kirby KA, Wang Z, Sarafianos SG. Huber AD, et al. Among authors: wang z. mSphere. 2018 Apr 18;3(2):e00131-18. doi: 10.1128/mSphereDirect.00131-18. Print 2018 Apr 25. mSphere. 2018. PMID: 29669885 Free PMC article.

2

Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited.

Tang J, Maddali K, Pommier Y, Sham YY, Wang Z. Tang J, et al. Among authors: wang z. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3275-9. doi: 10.1016/j.bmcl.2010.04.048. Epub 2010 Apr 21. Bioorg Med Chem Lett. 2010. PMID: 20457521 Free PMC article.

3

Pharmacophore and structure-activity relationships of integrase inhibition within a dual inhibitor scaffold of HIV reverse transcriptase and integrase.

Wang Z, Tang J, Salomon CE, Dreis CD, Vince R. Wang Z, et al. Bioorg Med Chem. 2010 Jun 15;18(12):4202-11. doi: 10.1016/j.bmc.2010.05.004. Epub 2010 May 7. Bioorg Med Chem. 2010. PMID: 20576573

4

3-Hydroxypyrimidine-2,4-diones as an inhibitor scaffold of HIV integrase.

Tang J, Maddali K, Metifiot M, Sham YY, Vince R, Pommier Y, Wang Z. Tang J, et al. Among authors: wang z. J Med Chem. 2011 Apr 14;54(7):2282-92. doi: 10.1021/jm1014378. Epub 2011 Mar 7. J Med Chem. 2011. PMID: 21381765 Free PMC article.

5

6-Benzoyl-3-hydroxypyrimidine-2,4-diones as dual inhibitors of HIV reverse transcriptase and integrase.

Tang J, Maddali K, Dreis CD, Sham YY, Vince R, Pommier Y, Wang Z. Tang J, et al. Among authors: wang z. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2400-2. doi: 10.1016/j.bmcl.2011.02.069. Epub 2011 Feb 18. Bioorg Med Chem Lett. 2011. PMID: 21392991 Free PMC article.

6

N-3 Hydroxylation of Pyrimidine-2,4-diones Yields Dual Inhibitors of HIV Reverse Transcriptase and Integrase.

Tang J, Maddali K, Dreis CD, Sham YY, Vince R, Pommier Y, Wang Z. Tang J, et al. Among authors: wang z. ACS Med Chem Lett. 2011 Jan;2(1):63-67. doi: 10.1021/ml1002162. ACS Med Chem Lett. 2011. PMID: 21499541 Free PMC article.

7

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus.

Chen YL, Tang J, Kesler MJ, Sham YY, Vince R, Geraghty RJ, Wang Z. Chen YL, et al. Among authors: wang z. Bioorg Med Chem. 2012 Jan 1;20(1):467-79. doi: 10.1016/j.bmc.2011.10.058. Epub 2011 Oct 24. Bioorg Med Chem. 2012. PMID: 22100256

8

Structural and inhibition studies of the RNase H function of xenotropic murine leukemia virus-related virus reverse transcriptase.

Kirby KA, Marchand B, Ong YT, Ndongwe TP, Hachiya A, Michailidis E, Leslie MD, Sietsema DV, Fetterly TL, Dorst CA, Singh K, Wang Z, Parniak MA, Sarafianos SG. Kirby KA, et al. Among authors: wang z. Antimicrob Agents Chemother. 2012 Apr;56(4):2048-61. doi: 10.1128/AAC.06000-11. Epub 2012 Jan 17. Antimicrob Agents Chemother. 2012. PMID: 22252812 Free PMC article.

9

Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1,3-diones: dual inhibition against HIV reverse transcriptase-associated RNase H and polymerase with antiviral activities.

Vernekar SK, Liu Z, Nagy E, Miller L, Kirby KA, Wilson DJ, Kankanala J, Sarafianos SG, Parniak MA, Wang Z. Vernekar SK, et al. Among authors: wang z. J Med Chem. 2015 Jan 22;58(2):651-64. doi: 10.1021/jm501132s. Epub 2014 Dec 30. J Med Chem. 2015. PMID: 25522204 Free PMC article.

10

3-Hydroxypyrimidine-2,4-diones as Selective Active Site Inhibitors of HIV Reverse Transcriptase-Associated RNase H: Design, Synthesis, and Biochemical Evaluations.

Tang J, Liu F, Nagy E, Miller L, Kirby KA, Wilson DJ, Wu B, Sarafianos SG, Parniak MA, Wang Z. Tang J, et al. Among authors: wang z. J Med Chem. 2016 Mar 24;59(6):2648-59. doi: 10.1021/acs.jmedchem.5b01879. Epub 2016 Mar 8. J Med Chem. 2016. PMID: 26927866 Free PMC article.

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