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Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression.
Jantsch J, Wiese M, Schödel J, Castiglione K, Gläsner J, Kolbe S, Mole D, Schleicher U, Eckardt KU, Hensel M, Lang R, Bogdan C, Schnare M, Willam C. Jantsch J, et al. Among authors: lang r. J Leukoc Biol. 2011 Sep;90(3):551-62. doi: 10.1189/jlb.1210683. Epub 2011 Jun 17. J Leukoc Biol. 2011. PMID: 21685248
Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen.
Siegert I, Schödel J, Nairz M, Schatz V, Dettmer K, Dick C, Kalucka J, Franke K, Ehrenschwender M, Schley G, Beneke A, Sutter J, Moll M, Hellerbrand C, Wielockx B, Katschinski DM, Lang R, Galy B, Hentze MW, Koivunen P, Oefner PJ, Bogdan C, Weiss G, Willam C, Jantsch J. Siegert I, et al. Among authors: lang r. Cell Rep. 2015 Dec 15;13(10):2048-55. doi: 10.1016/j.celrep.2015.11.005. Epub 2015 Nov 25. Cell Rep. 2015. PMID: 26628374 Free article.
Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever.
Kohl L, Siddique MNAA, Bodendorfer B, Berger R, Preikschat A, Daniel C, Ölke M, Liebler-Tenorio E, Schulze-Luehrmann J, Mauermeir M, Yang KT, Hayek I, Szperlinski M, Andrack J, Schleicher U, Bozec A, Krönke G, Murray PJ, Wirtz S, Yamamoto M, Schatz V, Jantsch J, Oefner P, Degrandi D, Pfeffer K, Mertens-Scholz K, Rauber S, Bogdan C, Dettmer K, Lührmann A, Lang R. Kohl L, et al. Among authors: lang r. EMBO Mol Med. 2023 Feb 8;15(2):e15931. doi: 10.15252/emmm.202215931. Epub 2022 Dec 7. EMBO Mol Med. 2023. PMID: 36479617 Free PMC article.
2,608 results