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Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models.
Esquejo RM, Salatto CT, Delmore J, Albuquerque B, Reyes A, Shi Y, Moccia R, Cokorinos E, Peloquin M, Monetti M, Barricklow J, Bollinger E, Smith BK, Day EA, Nguyen C, Geoghegan KF, Kreeger JM, Opsahl A, Ward J, Kalgutkar AS, Tess D, Butler L, Shirai N, Osborne TF, Steinberg GR, Birnbaum MJ, Cameron KO, Miller RA. Esquejo RM, et al. Among authors: nguyen c. EBioMedicine. 2018 May;31:122-132. doi: 10.1016/j.ebiom.2018.04.009. Epub 2018 Apr 8. EBioMedicine. 2018. PMID: 29673898 Free PMC article.
Mapping the Binding Site of BMS-708163 on γ-Secretase with Cleavable Photoprobes.
Gertsik N, Am Ende CW, Geoghegan KF, Nguyen C, Mukherjee P, Mente S, Seneviratne U, Johnson DS, Li YM. Gertsik N, et al. Among authors: nguyen c. Cell Chem Biol. 2017 Jan 19;24(1):3-8. doi: 10.1016/j.chembiol.2016.12.006. Epub 2017 Jan 5. Cell Chem Biol. 2017. PMID: 28065657 Free PMC article.
MAP4K4 Is a Threonine Kinase That Phosphorylates FARP1.
Schwaid AG, Su C, Loos P, Wu J, Nguyen C, Stone KL, Kanyo J, Geoghegan KF, Bhattacharya SK, Dow RL, Buckbinder L, Carpino PA. Schwaid AG, et al. Among authors: nguyen c. ACS Chem Biol. 2015 Dec 18;10(12):2667-71. doi: 10.1021/acschembio.5b00679. Epub 2015 Sep 30. ACS Chem Biol. 2015. PMID: 26422651
PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor.
Xu H, Jesson MI, Seneviratne UI, Lin TH, Sharif MN, Xue L, Nguyen C, Everley RA, Trujillo JI, Johnson DS, Point GR, Thorarensen A, Kilty I, Telliez JB. Xu H, et al. Among authors: nguyen c. ACS Chem Biol. 2019 Jun 21;14(6):1235-1242. doi: 10.1021/acschembio.9b00188. Epub 2019 May 22. ACS Chem Biol. 2019. PMID: 31082193
Delineating the role of cooperativity in the design of potent PROTACs for BTK.
Zorba A, Nguyen C, Xu Y, Starr J, Borzilleri K, Smith J, Zhu H, Farley KA, Ding W, Schiemer J, Feng X, Chang JS, Uccello DP, Young JA, Garcia-Irrizary CN, Czabaniuk L, Schuff B, Oliver R, Montgomery J, Hayward MM, Coe J, Chen J, Niosi M, Luthra S, Shah JC, El-Kattan A, Qiu X, West GM, Noe MC, Shanmugasundaram V, Gilbert AM, Brown MF, Calabrese MF. Zorba A, et al. Among authors: nguyen c. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7285-E7292. doi: 10.1073/pnas.1803662115. Epub 2018 Jul 16. Proc Natl Acad Sci U S A. 2018. PMID: 30012605 Free PMC article.
Flexible Electrode Arrays Based on a Wide Bandgap Semiconductors for Chronic Implantable Multiplexed Sensing and Heart Pacemakers.
Truong TA, Huang X, Barton M, Ashok A, Al Abed A, Almasri R, Shivdasanic MN, Reshamwala R, Ingles J, Thai MT, Nguyen CC, Zhao S, Zhang X, Gu Z, Vasanth A, Peng S, Nguyen TK, Do N, Nguyen NT, Zhao H, Phan HP. Truong TA, et al. Among authors: nguyen cc. ACS Nano. 2025 Jan 3. doi: 10.1021/acsnano.4c15294. Online ahead of print. ACS Nano. 2025. PMID: 39752298
4,702 results