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Page 1
Effective treatment of refractory CMV reactivation after allogeneic stem cell transplantation with in vitro-generated CMV pp65-specific CD8+ T-cell lines.
Meij P, Jedema I, Zandvliet ML, van der Heiden PL, van de Meent M, van Egmond HM, van Liempt E, Hoogstraten C, Kruithof S, Veld S, Marijt EW, von dem Borne PA, Lankester AC, Halkes CJ, Falkenburg JH. Meij P, et al. Among authors: van egmond hm. J Immunother. 2012 Oct;35(8):621-8. doi: 10.1097/CJI.0b013e31826e35f6. J Immunother. 2012. PMID: 22996368 Clinical Trial.
High Mutation Frequency of the PIGA Gene in T Cells Results in Reconstitution of GPI Anchor-/CD52- T Cells That Can Give Early Immune Protection after Alemtuzumab-Based T Cell-Depleted Allogeneic Stem Cell Transplantation.
Loeff FC, Falkenburg JHF, Hageman L, Huisman W, Veld SAJ, van Egmond HME, van de Meent M, von dem Borne PA, Veelken H, Halkes CJM, Jedema I. Loeff FC, et al. Among authors: van egmond hme. J Immunol. 2018 Mar 15;200(6):2199-2208. doi: 10.4049/jimmunol.1701018. Epub 2018 Feb 2. J Immunol. 2018. PMID: 29427418
Direct cloning of leukemia-reactive T cells from patients treated with donor lymphocyte infusion shows a relative dominance of hematopoiesis-restricted minor histocompatibility antigen HA-1 and HA-2 specific T cells.
Kloosterboer FM, van Luxemburg-Heijs SA, van Soest RA, Barbui AM, van Egmond HM, Strijbosch MP, Kester MG, Marijt WA, Goulmy E, Willemze R, Falkenburg JH. Kloosterboer FM, et al. Among authors: van egmond hm, van soest ra, van luxemburg heijs sa. Leukemia. 2004 Apr;18(4):798-808. doi: 10.1038/sj.leu.2403297. Leukemia. 2004. PMID: 14973499
HA-1H T-Cell Receptor Gene Transfer to Redirect Virus-Specific T Cells for Treatment of Hematological Malignancies After Allogeneic Stem Cell Transplantation: A Phase 1 Clinical Study.
van Balen P, Jedema I, van Loenen MM, de Boer R, van Egmond HM, Hagedoorn RS, Hoogstaten C, Veld SAJ, Hageman L, van Liempt PAG, Zwaginga JJ, Meij P, Veelken H, Falkenburg JHF, Heemskerk MHM. van Balen P, et al. Among authors: van egmond hm. Front Immunol. 2020 Aug 20;11:1804. doi: 10.3389/fimmu.2020.01804. eCollection 2020. Front Immunol. 2020. PMID: 32973756 Free PMC article. Clinical Trial.
Complement-dependent cytotoxicity induced by therapeutic antibodies in B-cell acute lymphoblastic leukemia is dictated by target antigen expression levels and augmented by loss of membrane-bound complement inhibitors.
Loeff FC, van Egmond HME, Nijmeijer BA, Falkenburg JHF, Halkes CJ, Jedema I. Loeff FC, et al. Among authors: van egmond hme. Leuk Lymphoma. 2017 Sep;58(9):1-14. doi: 10.1080/10428194.2017.1281411. Epub 2017 Jan 31. Leuk Lymphoma. 2017. PMID: 28140725
Minor histocompatibility antigen-specific T cells with multiple distinct specificities can be isolated by direct cloning of IFNgamma-secreting T cells from patients with relapsed leukemia responding to donor lymphocyte infusion.
Kloosterboer FM, van Luxemburg-Heijs SA, van Soest RA, van Egmond HM, Barbui AM, Strijbosch MP, Willemze R, Falkenburg JH. Kloosterboer FM, et al. Among authors: van egmond hm. Leukemia. 2005 Jan;19(1):83-90. doi: 10.1038/sj.leu.2403572. Leukemia. 2005. PMID: 15526024
Tracking the progeny of adoptively transferred virus-specific T cells in patients posttransplant using TCR sequencing.
Huisman W, Roex MCJ, Hageman L, Koster EAS, Veld SAJ, Hoogstraten C, van Balen P, van Egmond HM, van Bergen CAM, Einsele H, Germeroth L, Amsen D, Falkenburg JHF, Jedema I. Huisman W, et al. Among authors: van egmond hm. Blood Adv. 2023 Mar 14;7(5):812-827. doi: 10.1182/bloodadvances.2022007270. Blood Adv. 2023. PMID: 36121440 Free PMC article.
Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application.
Griffioen M, van Egmond HM, Barnby-Porritt H, van der Hoorn MA, Hagedoorn RS, Kester MG, Schwabe N, Willemze R, Falkenburg JH, Heemskerk MH. Griffioen M, et al. Among authors: van egmond hm. Haematologica. 2008 Oct;93(10):1535-43. doi: 10.3324/haematol.13067. Epub 2008 Sep 2. Haematologica. 2008. PMID: 18768532 Free article.
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