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TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease.
Liu YL, Reeves HL, Burt AD, Tiniakos D, McPherson S, Leathart JB, Allison ME, Alexander GJ, Piguet AC, Anty R, Donaldson P, Aithal GP, Francque S, Van Gaal L, Clement K, Ratziu V, Dufour JF, Day CP, Daly AK, Anstee QM. Liu YL, et al. Among authors: alexander gj. Nat Commun. 2014 Jun 30;5:4309. doi: 10.1038/ncomms5309. Nat Commun. 2014. PMID: 24978903 Free PMC article.
Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection.
Huang H, Duggal P, Thio CL, Latanich R, Goedert JJ, Mangia A, Cox AL, Kirk GD, Mehta S, Aneja J, Alric L, Donfield SM, Cramp ME, Khakoo SI, Tobler LH, Busch M, Alexander GJ, Rosen HR, Edlin BR, Segal FP, Lauer GM, Thomas DL, Daly MJ, Chung RT, Kim AY. Huang H, et al. Among authors: alexander gj. Sci Rep. 2017 Nov 20;7(1):15843. doi: 10.1038/s41598-017-16011-2. Sci Rep. 2017. PMID: 29158528 Free PMC article.
Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis.
Owen NE, Alexander GJ, Sen S, Bunclark K, Polwarth G, Pepke-Zaba J, Davenport AP, Morrell NW, Upton PD. Owen NE, et al. Among authors: alexander gj. EBioMedicine. 2020 Jun;56:102794. doi: 10.1016/j.ebiom.2020.102794. Epub 2020 May 23. EBioMedicine. 2020. PMID: 32454407 Free PMC article.
Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.
Mells GF, Floyd JA, Morley KI, Cordell HJ, Franklin CS, Shin SY, Heneghan MA, Neuberger JM, Donaldson PT, Day DB, Ducker SJ, Muriithi AW, Wheater EF, Hammond CJ, Dawwas MF; UK PBC Consortium; Wellcome Trust Case Control Consortium 3; Jones DE, Peltonen L, Alexander GJ, Sandford RN, Anderson CA. Mells GF, et al. Among authors: alexander gj. Nat Genet. 2011 Mar 13;43(4):329-32. doi: 10.1038/ng.789. Nat Genet. 2011. PMID: 21399635 Free PMC article.
Unacceptable failures: the final report of the Lancet Commission into liver disease in the UK.
Williams R, Aithal G, Alexander GJ, Allison M, Armstrong I, Aspinall R, Baker A, Batterham R, Brown K, Burton R, Cramp ME, Day N, Dhawan A, Drummond C, Ferguson J, Foster G, Gilmore I, Greenberg J, Henn C, Jarvis H, Kelly D, Mathews M, McCloud A, MacGilchrist A, McKee M, Moriarty K, Morling J, Newsome P, Rice P, Roberts S, Rutter H, Samyn M, Severi K, Sheron N, Thorburn D, Verne J, Vohra J, Williams J, Yeoman A. Williams R, et al. Among authors: alexander gj. Lancet. 2020 Jan 18;395(10219):226-239. doi: 10.1016/S0140-6736(19)32908-3. Epub 2019 Nov 29. Lancet. 2020. PMID: 31791690 Review.
Sex and age are determinants of the clinical phenotype of primary biliary cirrhosis and response to ursodeoxycholic acid.
Carbone M, Mells GF, Pells G, Dawwas MF, Newton JL, Heneghan MA, Neuberger JM, Day DB, Ducker SJ; UK PBC Consortium; Sandford RN, Alexander GJ, Jones DE. Carbone M, et al. Among authors: alexander gj. Gastroenterology. 2013 Mar;144(3):560-569.e7; quiz e13-4. doi: 10.1053/j.gastro.2012.12.005. Epub 2012 Dec 12. Gastroenterology. 2013. PMID: 23246637
386 results