Svensson RJ - Search Results

1

Greater Early Bactericidal Activity at Higher Rifampicin Doses Revealed by Modeling and Clinical Trial Simulations.

Svensson RJ, Svensson EM, Aarnoutse RE, Diacon AH, Dawson R, Gillespie SH, Moodley M, Boeree MJ, Simonsson USH. Svensson RJ, et al. Among authors: svensson em. J Infect Dis. 2018 Aug 14;218(6):991-999. doi: 10.1093/infdis/jiy242. J Infect Dis. 2018. PMID: 29718390 Clinical Trial.

2

Application of the Multistate Tuberculosis Pharmacometric Model in Patients With Rifampicin-Treated Pulmonary Tuberculosis.

Svensson RJ, Simonsson U. Svensson RJ, et al. CPT Pharmacometrics Syst Pharmacol. 2016 May;5(5):264-73. doi: 10.1002/psp4.12079. Epub 2016 May 17. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27299939 Free PMC article.

3

Improved power for TB Phase IIa trials using a model-based pharmacokinetic-pharmacodynamic approach compared with commonly used analysis methods.

Svensson RJ, Gillespie SH, Simonsson USH. Svensson RJ, et al. J Antimicrob Chemother. 2017 Aug 1;72(8):2311-2319. doi: 10.1093/jac/dkx129. J Antimicrob Chemother. 2017. PMID: 28520930 Free PMC article.

4

A Population Pharmacokinetic Model Incorporating Saturable Pharmacokinetics and Autoinduction for High Rifampicin Doses.

Svensson RJ, Aarnoutse RE, Diacon AH, Dawson R, Gillespie SH, Boeree MJ, Simonsson USH. Svensson RJ, et al. Clin Pharmacol Ther. 2018 Apr;103(4):674-683. doi: 10.1002/cpt.778. Epub 2017 Aug 7. Clin Pharmacol Ther. 2018. PMID: 28653479 Free PMC article.

5

Improving treatment outcome assessment in a mouse tuberculosis model.

Mourik BC, Svensson RJ, de Knegt GJ, Bax HI, Verbon A, Simonsson USH, de Steenwinkel JEM. Mourik BC, et al. Among authors: svensson rj. Sci Rep. 2018 Apr 9;8(1):5714. doi: 10.1038/s41598-018-24067-x. Sci Rep. 2018. PMID: 29632372 Free PMC article.

6

Forecasting Clinical Dose-Response From Preclinical Studies in Tuberculosis Research: Translational Predictions With Rifampicin.

Wicha SG, Clewe O, Svensson RJ, Gillespie SH, Hu Y, Coates ARM, Simonsson USH. Wicha SG, et al. Among authors: svensson rj. Clin Pharmacol Ther. 2018 Dec;104(6):1208-1218. doi: 10.1002/cpt.1102. Epub 2018 Jun 19. Clin Pharmacol Ther. 2018. PMID: 29700814 Free PMC article.

7

The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis.

Svensson EM, Svensson RJ, Te Brake LHM, Boeree MJ, Heinrich N, Konsten S, Churchyard G, Dawson R, Diacon AH, Kibiki GS, Minja LT, Ntingiya NE, Sanne I, Gillespie SH, Hoelscher M, Phillips PPJ, Simonsson USH, Aarnoutse R. Svensson EM, et al. Among authors: svensson rj. Clin Infect Dis. 2018 Jun 18;67(1):34-41. doi: 10.1093/cid/ciy026. Clin Infect Dis. 2018. PMID: 29917079 Free PMC article.

8

Individualised dosing algorithm and personalised treatment of high-dose rifampicin for tuberculosis.

Svensson RJ, Niward K, Davies Forsman L, Bruchfeld J, Paues J, Eliasson E, Schön T, Simonsson USH. Svensson RJ, et al. Br J Clin Pharmacol. 2019 Oct;85(10):2341-2350. doi: 10.1111/bcp.14048. Epub 2019 Jul 25. Br J Clin Pharmacol. 2019. PMID: 31269277 Free PMC article.

9

Model-Based Relationship between the Molecular Bacterial Load Assay and Time to Positivity in Liquid Culture.

Svensson RJ, Sabiiti W, Kibiki GS, Ntinginya NE, Bhatt N, Davies G, Gillespie SH, Simonsson USH. Svensson RJ, et al. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e00652-19. doi: 10.1128/AAC.00652-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31358585 Free PMC article.

10

Rifampicin Can Be Given as Flat-Dosing Instead of Weight-Band Dosing.

Susanto BO, Svensson RJ, Svensson EM, Aarnoutse R, Boeree MJ, Simonsson USH. Susanto BO, et al. Among authors: svensson rj. Clin Infect Dis. 2020 Dec 15;71(12):3055-3060. doi: 10.1093/cid/ciz1202. Clin Infect Dis. 2020. PMID: 31867594 Free PMC article.

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