Rohrs JA - Search Results

1

CAR-T Cells Surface-Engineered with Drug-Encapsulated Nanoparticles Can Ameliorate Intratumoral T-cell Hypofunction.

Siriwon N, Kim YJ, Siegler E, Chen X, Rohrs JA, Liu Y, Wang P. Siriwon N, et al. Among authors: rohrs ja. Cancer Immunol Res. 2018 Jul;6(7):812-824. doi: 10.1158/2326-6066.CIR-17-0502. Epub 2018 May 2. Cancer Immunol Res. 2018. PMID: 29720380

2

Combination Cancer Therapy Using Chimeric Antigen Receptor-Engineered Natural Killer Cells as Drug Carriers.

Siegler EL, Kim YJ, Chen X, Siriwon N, Mac J, Rohrs JA, Bryson PD, Wang P. Siegler EL, et al. Among authors: rohrs ja. Mol Ther. 2017 Dec 6;25(12):2607-2619. doi: 10.1016/j.ymthe.2017.08.010. Epub 2017 Aug 19. Mol Ther. 2017. PMID: 28919377 Free PMC article.

3

Combination drug delivery via multilamellar vesicles enables targeting of tumor cells and tumor vasculature.

Liu Y, Kim YJ, Siriwon N, Rohrs JA, Yu Z, Wanga P. Liu Y, et al. Among authors: rohrs ja. Biotechnol Bioeng. 2018 Jun;115(6):1403-1415. doi: 10.1002/bit.26566. Epub 2018 Mar 6. Biotechnol Bioeng. 2018. PMID: 29457630

4

Generation of Targeted Adeno-Associated Virus (AAV) Vectors for Human Gene Therapy.

Liu Y, Siriwon N, Rohrs JA, Wang P. Liu Y, et al. Among authors: rohrs ja. Curr Pharm Des. 2015;21(22):3248-56. doi: 10.2174/1381612821666150531171653. Curr Pharm Des. 2015. PMID: 26027561 Review.

5

In Vivo Expansion and Antitumor Activity of Coinfused CD28- and 4-1BB-Engineered CAR-T Cells in Patients with B Cell Leukemia.

Cheng Z, Wei R, Ma Q, Shi L, He F, Shi Z, Jin T, Xie R, Wei B, Chen J, Fang H, Han X, Rohrs JA, Bryson P, Liu Y, Li QJ, Zhu B, Wang P. Cheng Z, et al. Among authors: rohrs ja. Mol Ther. 2018 Apr 4;26(4):976-985. doi: 10.1016/j.ymthe.2018.01.022. Epub 2018 Feb 2. Mol Ther. 2018. PMID: 29503204 Free PMC article. Clinical Trial.

6

Understanding the Dynamics of T-Cell Activation in Health and Disease Through the Lens of Computational Modeling.

Rohrs JA, Wang P, Finley SD. Rohrs JA, et al. JCO Clin Cancer Inform. 2019 Jan;3:1-8. doi: 10.1200/CCI.18.00057. JCO Clin Cancer Inform. 2019. PMID: 30689404 Free PMC article. Review.

7

ERK Activation in CAR T Cells Is Amplified by CD28-Mediated Increase in CD3ζ Phosphorylation.

Rohrs JA, Siegler EL, Wang P, Finley SD. Rohrs JA, et al. iScience. 2020 Apr 24;23(4):101023. doi: 10.1016/j.isci.2020.101023. Epub 2020 Mar 30. iScience. 2020. PMID: 32325413 Free PMC article.

8

Advances and challenges in the use of nanoparticles to optimize PK/PD interactions of combined anti-cancer therapies.

Liu Y, Rohrs J, Wang P. Liu Y, et al. Curr Drug Metab. 2014;15(8):818-28. doi: 10.2174/1389200216666150223152958. Curr Drug Metab. 2014. PMID: 25705903 Review.

9

Co-Eradication of Breast Cancer Cells and Cancer Stem Cells by Cross-Linked Multilamellar Liposomes Enhances Tumor Treatment.

Kim YJ, Liu Y, Li S, Rohrs J, Zhang R, Zhang X, Wang P. Kim YJ, et al. Mol Pharm. 2015 Aug 3;12(8):2811-22. doi: 10.1021/mp500754r. Epub 2015 Jul 1. Mol Pharm. 2015. PMID: 26098197

10

Predictive Model of Lymphocyte-Specific Protein Tyrosine Kinase (LCK) Autoregulation.

Rohrs JA, Wang P, Finley SD. Rohrs JA, et al. Cell Mol Bioeng. 2016;9:351-367. doi: 10.1007/s12195-016-0438-7. Epub 2016 Apr 26. Cell Mol Bioeng. 2016. PMID: 27547268 Free PMC article.

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