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WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis.
Biswas A, Shouval DS, Griffith A, Goettel JA, Field M, Kang YH, Konnikova L, Janssen E, Redhu NS, Thrasher AJ, Chatila T, Kuchroo VK, Geha RS, Notarangelo LD, Pai SY, Horwitz BH, Snapper SB. Biswas A, et al. Among authors: thrasher aj. Nat Commun. 2018 May 3;9(1):1779. doi: 10.1038/s41467-018-03670-6. Nat Commun. 2018. PMID: 29725003 Free PMC article.
Mechanisms of WASp-mediated hematologic and immunologic disease.
Burns S, Cory GO, Vainchenker W, Thrasher AJ. Burns S, et al. Among authors: thrasher aj. Blood. 2004 Dec 1;104(12):3454-62. doi: 10.1182/blood-2004-04-1678. Epub 2004 Aug 12. Blood. 2004. PMID: 15308573 Free article. Review.
Long-term outcome following hematopoietic stem-cell transplantation in Wiskott-Aldrich syndrome: collaborative study of the European Society for Immunodeficiencies and European Group for Blood and Marrow Transplantation.
Ozsahin H, Cavazzana-Calvo M, Notarangelo LD, Schulz A, Thrasher AJ, Mazzolari E, Slatter MA, Le Deist F, Blanche S, Veys P, Fasth A, Bredius R, Sedlacek P, Wulffraat N, Ortega J, Heilmann C, O'Meara A, Wachowiak J, Kalwak K, Matthes-Martin S, Gungor T, Ikinciogullari A, Landais P, Cant AJ, Friedrich W, Fischer A. Ozsahin H, et al. Among authors: thrasher aj. Blood. 2008 Jan 1;111(1):439-45. doi: 10.1182/blood-2007-03-076679. Epub 2007 Sep 27. Blood. 2008. PMID: 17901250 Free article.
Activating mutations of N-WASP alter Shigella pathogenesis.
Adamovich DA, Nakamura F, Worth A, Burns S, Thrasher AJ, Hartwig JH, Snapper SB. Adamovich DA, et al. Among authors: thrasher aj. Biochem Biophys Res Commun. 2009 Jul 3;384(3):284-9. doi: 10.1016/j.bbrc.2009.04.050. Epub 2009 Apr 18. Biochem Biophys Res Commun. 2009. PMID: 19379711 Free PMC article.
Phosphorylation of WASp is a key regulator of activity and stability in vivo.
Blundell MP, Bouma G, Metelo J, Worth A, Calle Y, Cowell LA, Westerberg LS, Moulding DA, Mirando S, Kinnon C, Cory GO, Jones GE, Snapper SB, Burns SO, Thrasher AJ. Blundell MP, et al. Among authors: thrasher aj. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15738-43. doi: 10.1073/pnas.0904346106. Epub 2009 Sep 1. Proc Natl Acad Sci U S A. 2009. PMID: 19805221 Free PMC article.
WASP: a key immunological multitasker.
Thrasher AJ, Burns SO. Thrasher AJ, et al. Nat Rev Immunol. 2010 Mar;10(3):182-92. doi: 10.1038/nri2724. Nat Rev Immunol. 2010. PMID: 20182458 Review.
Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes.
Westerberg LS, Meelu P, Baptista M, Eston MA, Adamovich DA, Cotta-de-Almeida V, Seed B, Rosen MK, Vandenberghe P, Thrasher AJ, Klein C, Alt FW, Snapper SB. Westerberg LS, et al. Among authors: thrasher aj. J Exp Med. 2010 Jun 7;207(6):1145-52. doi: 10.1084/jem.20091245. Epub 2010 May 31. J Exp Med. 2010. PMID: 20513746 Free PMC article.
439 results