Thomas PJ - Search Results

1

Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization.

Pinarbasi ES, Cağatay T, Fung HYJ, Li YC, Chook YM, Thomas PJ. Pinarbasi ES, et al. Among authors: thomas pj. Sci Rep. 2018 May 4;8(1):7083. doi: 10.1038/s41598-018-25008-4. Sci Rep. 2018. PMID: 29728608 Free PMC article.

2

Pathogenic Signal Sequence Mutations in Progranulin Disrupt SRP Interactions Required for mRNA Stability.

Pinarbasi ES, Karamyshev AL, Tikhonova EB, Wu IH, Hudson H, Thomas PJ. Pinarbasi ES, et al. Among authors: thomas pj. Cell Rep. 2018 Jun 5;23(10):2844-2851. doi: 10.1016/j.celrep.2018.05.003. Cell Rep. 2018. PMID: 29874572 Free PMC article.

3

A unique redox-sensing sensor II motif in TorsinA plays a critical role in nucleotide and partner binding.

Zhu L, Millen L, Mendoza JL, Thomas PJ. Zhu L, et al. Among authors: thomas pj. J Biol Chem. 2010 Nov 26;285(48):37271-80. doi: 10.1074/jbc.M110.123471. Epub 2010 Sep 22. J Biol Chem. 2010. PMID: 20861018 Free PMC article.

4

TDP-43 identified from a genome wide RNAi screen for SOD1 regulators.

Somalinga BR, Day CE, Wei S, Roth MG, Thomas PJ. Somalinga BR, et al. Among authors: thomas pj. PLoS One. 2012;7(4):e35818. doi: 10.1371/journal.pone.0035818. Epub 2012 Apr 26. PLoS One. 2012. PMID: 22563406 Free PMC article.

5

A screen to identify cellular modulators of soluble levels of an amyotrophic lateral sclerosis (ALS)-causing mutant SOD1.

Somalinga BR, Miller GA, Malik HT, Wigley WC, Thomas PJ. Somalinga BR, et al. Among authors: thomas pj. J Biomol Screen. 2011 Oct;16(9):974-85. doi: 10.1177/1087057111418505. Epub 2011 Aug 29. J Biomol Screen. 2011. PMID: 21875953 Free PMC article.

6

The cystic fibrosis-causing mutation deltaF508 affects multiple steps in cystic fibrosis transmembrane conductance regulator biogenesis.

Thibodeau PH, Richardson JM 3rd, Wang W, Millen L, Watson J, Mendoza JL, Du K, Fischman S, Senderowitz H, Lukacs GL, Kirk K, Thomas PJ. Thibodeau PH, et al. Among authors: thomas pj. J Biol Chem. 2010 Nov 12;285(46):35825-35. doi: 10.1074/jbc.M110.131623. Epub 2010 Jul 28. J Biol Chem. 2010. PMID: 20667826 Free PMC article.

7

N-Alpha-Acetyltransferases and Regulation of CFTR Expression.

Vetter AJ, Karamyshev AL, Patrick AE, Hudson H, Thomas PJ. Vetter AJ, et al. Among authors: thomas pj. PLoS One. 2016 May 16;11(5):e0155430. doi: 10.1371/journal.pone.0155430. eCollection 2016. PLoS One. 2016. PMID: 27182737 Free PMC article.

8

Localization and suppression of a kinetic defect in cystic fibrosis transmembrane conductance regulator folding.

Qu BH, Strickland EH, Thomas PJ. Qu BH, et al. Among authors: thomas pj. J Biol Chem. 1997 Jun 20;272(25):15739-44. doi: 10.1074/jbc.272.25.15739. J Biol Chem. 1997. PMID: 9188468 Free article.

9

Inefficient SRP interaction with a nascent chain triggers a mRNA quality control pathway.

Karamyshev AL, Patrick AE, Karamysheva ZN, Griesemer DS, Hudson H, Tjon-Kon-Sang S, Nilsson I, Otto H, Liu Q, Rospert S, von Heijne G, Johnson AE, Thomas PJ. Karamyshev AL, et al. Among authors: thomas pj. Cell. 2014 Jan 16;156(1-2):146-57. doi: 10.1016/j.cell.2013.12.017. Cell. 2014. PMID: 24439374 Free PMC article.

10

Side chain and backbone contributions of Phe508 to CFTR folding.

Thibodeau PH, Brautigam CA, Machius M, Thomas PJ. Thibodeau PH, et al. Among authors: thomas pj. Nat Struct Mol Biol. 2005 Jan;12(1):10-6. doi: 10.1038/nsmb881. Epub 2004 Dec 26. Nat Struct Mol Biol. 2005. PMID: 15619636 Free PMC article.

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