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A new strategy to identify hepatitis B virus entry inhibitors by AlphaScreen technology targeting the envelope-receptor interaction.
Saso W, Tsukuda S, Ohashi H, Fukano K, Morishita R, Matsunaga S, Ohki M, Ryo A, Park SY, Suzuki R, Aizaki H, Muramatsu M, Sureau C, Wakita T, Matano T, Watashi K. Saso W, et al. Among authors: park sy. Biochem Biophys Res Commun. 2018 Jun 22;501(2):374-379. doi: 10.1016/j.bbrc.2018.04.187. Epub 2018 May 11. Biochem Biophys Res Commun. 2018. PMID: 29730285
A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide.
Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T. Kaneko M, et al. Among authors: park sy. J Virol. 2015 Dec;89(23):11945-53. doi: 10.1128/JVI.01855-15. Epub 2015 Sep 16. J Virol. 2015. PMID: 26378168 Free PMC article.
Cyclosporin derivatives inhibit hepatitis B virus entry without interfering with NTCP transporter activity.
Shimura S, Watashi K, Fukano K, Peel M, Sluder A, Kawai F, Iwamoto M, Tsukuda S, Takeuchi JS, Miyake T, Sugiyama M, Ogasawara Y, Park SY, Tanaka Y, Kusuhara H, Mizokami M, Sureau C, Wakita T. Shimura S, et al. Among authors: park sy. J Hepatol. 2017 Apr;66(4):685-692. doi: 10.1016/j.jhep.2016.11.009. Epub 2016 Nov 25. J Hepatol. 2017. PMID: 27890789 Free PMC article.
Molecular mechanism of photoactivation of a light-regulated adenylate cyclase.
Ohki M, Sato-Tomita A, Matsunaga S, Iseki M, Tame JRH, Shibayama N, Park SY. Ohki M, et al. Among authors: park sy. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8562-8567. doi: 10.1073/pnas.1704391114. Epub 2017 Jul 24. Proc Natl Acad Sci U S A. 2017. PMID: 28739908 Free PMC article.
Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide.
Kaneko M, Futamura Y, Tsukuda S, Kondoh Y, Sekine T, Hirano H, Fukano K, Ohashi H, Saso W, Morishita R, Matsunaga S, Kawai F, Ryo A, Park SY, Suzuki R, Aizaki H, Ohtani N, Sureau C, Wakita T, Osada H, Watashi K. Kaneko M, et al. Among authors: park sy. Sci Rep. 2018 Feb 9;8(1):2769. doi: 10.1038/s41598-018-20987-w. Sci Rep. 2018. PMID: 29426822 Free PMC article.
Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization.
Iwamoto M, Saso W, Sugiyama R, Ishii K, Ohki M, Nagamori S, Suzuki R, Aizaki H, Ryo A, Yun JH, Park SY, Ohtani N, Muramatsu M, Iwami S, Tanaka Y, Sureau C, Wakita T, Watashi K. Iwamoto M, et al. Among authors: park sy. Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8487-8492. doi: 10.1073/pnas.1811064116. Epub 2019 Apr 5. Proc Natl Acad Sci U S A. 2019. PMID: 30952782 Free PMC article.
The machinery for endocytosis of epidermal growth factor receptor coordinates the transport of incoming hepatitis B virus to the endosomal network.
Iwamoto M, Saso W, Nishioka K, Ohashi H, Sugiyama R, Ryo A, Ohki M, Yun JH, Park SY, Ohshima T, Suzuki R, Aizaki H, Muramatsu M, Matano T, Iwami S, Sureau C, Wakita T, Watashi K. Iwamoto M, et al. Among authors: park sy. J Biol Chem. 2020 Jan 17;295(3):800-807. doi: 10.1074/jbc.AC119.010366. Epub 2019 Dec 12. J Biol Chem. 2020. PMID: 31836663 Free PMC article.
Direct observation of ligand migration within human hemoglobin at work.
Shibayama N, Sato-Tomita A, Ohki M, Ichiyanagi K, Park SY. Shibayama N, et al. Among authors: park sy. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4741-4748. doi: 10.1073/pnas.1913663117. Epub 2020 Feb 18. Proc Natl Acad Sci U S A. 2020. PMID: 32071219 Free PMC article.
8,035 results