O'Reilly TM - Search Results

1

Continuous low-dose infusion of patupilone increases the therapeutic index in mouse and rat tumour models.

Becquet M, Laborde L, Texier C, Sterker D, Gschwind HP, Pfaar U, Wartmann M, O'Reilly TM, McSheehy PM. Becquet M, et al. Among authors: o reilly tm. Anticancer Drugs. 2018 Aug;29(7):691-701. doi: 10.1097/CAD.0000000000000639. Anticancer Drugs. 2018. PMID: 29734209

2

Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo.

O'Reilly T, McSheehy PM, Wartmann M, Lassota P, Brandt R, Lane HA. O'Reilly T, et al. Anticancer Drugs. 2011 Jan;22(1):58-78. doi: 10.1097/CAD.0b013e3283400a20. Anticancer Drugs. 2011. PMID: 20890178

3

Pharmacokinetic profile of the microtubule stabilizer patupilone in tumor-bearing rodents and comparison of anti-cancer activity with other MTS in vitro and in vivo.

O'Reilly T, Wartmann M, Brueggen J, Allegrini PR, Floersheimer A, Maira M, McSheehy PM. O'Reilly T, et al. Cancer Chemother Pharmacol. 2008 Nov;62(6):1045-54. doi: 10.1007/s00280-008-0695-9. Epub 2008 Feb 27. Cancer Chemother Pharmacol. 2008. PMID: 18301895

4

Patupilone (epothilone B, EPO906) inhibits growth and metastasis of experimental prostate tumors in vivo.

O'Reilly T, McSheehy PM, Wenger F, Hattenberger M, Muller M, Vaxelaire J, Altmann KH, Wartmann M. O'Reilly T, et al. Prostate. 2005 Nov 1;65(3):231-40. doi: 10.1002/pros.20289. Prostate. 2005. PMID: 15948135

5

Patupilone induced vascular disruption in orthotopic rodent tumor models detected by magnetic resonance imaging and interstitial fluid pressure.

Ferretti S, Allegrini PR, O'Reilly T, Schnell C, Stumm M, Wartmann M, Wood J, McSheehy PM. Ferretti S, et al. Clin Cancer Res. 2005 Nov 1;11(21):7773-84. doi: 10.1158/1078-0432.CCR-05-1165. Clin Cancer Res. 2005. PMID: 16278399

6

Effects of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 on the tumor vasculature: implications for clinical imaging.

Schnell CR, Stauffer F, Allegrini PR, O'Reilly T, McSheehy PM, Dartois C, Stumm M, Cozens R, Littlewood-Evans A, García-Echeverría C, Maira SM. Schnell CR, et al. Cancer Res. 2008 Aug 15;68(16):6598-607. doi: 10.1158/0008-5472.CAN-08-1044. Cancer Res. 2008. PMID: 18701483

7

Everolimus and PTK/ZK show synergistic growth inhibition in the orthotopic BL16/BL6 murine melanoma model.

O'Reilly T, Lane HA, Wood JM, Schnell C, Littlewood-Evans A, Brueggen J, McSheehy PM. O'Reilly T, et al. Cancer Chemother Pharmacol. 2011 Jan;67(1):193-200. doi: 10.1007/s00280-010-1307-z. Epub 2010 May 30. Cancer Chemother Pharmacol. 2011. PMID: 20512579

8

4. The natural products epothilones A and B as lead structures for anticancer drug discovery: chemistry, biology, and SAR studies.

Altmann KH, Flörsheimer A, O'Reilly T, Wartmann M. Altmann KH, et al. Prog Med Chem. 2004;42:171-205. doi: 10.1016/S0079-6468(04)42004-9. Prog Med Chem. 2004. PMID: 15003721 Review. No abstract available.

9

Patupilone (epothilone B, EPO906) and imatinib (STI571, Glivec) in combination display enhanced antitumour activity in vivo against experimental rat C6 glioma.

O'Reilly T, Wartmann M, Maira SM, Hattenberger M, Vaxelaire J, Muller M, Ferretti S, Buchdunger E, Altmann KH, McSheehy PMJ. O'Reilly T, et al. Cancer Chemother Pharmacol. 2005 Apr;55(4):307-317. doi: 10.1007/s00280-004-0913-z. Epub 2004 Oct 26. Cancer Chemother Pharmacol. 2005. PMID: 15723258

10

Comparative pharmacokinetics of RAD001 (everolimus) in normal and tumor-bearing rodents.

O'Reilly T, McSheehy PM, Kawai R, Kretz O, McMahon L, Brueggen J, Bruelisauer A, Gschwind HP, Allegrini PR, Lane HA. O'Reilly T, et al. Cancer Chemother Pharmacol. 2010 Mar;65(4):625-39. doi: 10.1007/s00280-009-1068-8. Epub 2009 Sep 27. Cancer Chemother Pharmacol. 2010. PMID: 19784839

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