Freedman H - Search Results

1

A computational approach for predicting off-target toxicity of antiviral ribonucleoside analogues to mitochondrial RNA polymerase.

Freedman H, Winter P, Tuszynski J, Tyrrell DL, Houghton M. Freedman H, et al. J Biol Chem. 2018 Jun 22;293(25):9696-9705. doi: 10.1074/jbc.RA118.002588. Epub 2018 May 8. J Biol Chem. 2018. PMID: 29739852 Free PMC article.

2

Improving the performance of the coupled reference interaction site model-hyper-netted chain (RISM-HNC)/simulation method for free energy of solvation.

Freedman H, Le L, Tuszynski JA, Truong TN. Freedman H, et al. J Phys Chem B. 2008 Feb 28;112(8):2340-8. doi: 10.1021/jp077179l. Epub 2008 Feb 6. J Phys Chem B. 2008. PMID: 18251537

3

A unique mode of microtubule stabilization induced by peloruside A.

Huzil JT, Chik JK, Slysz GW, Freedman H, Tuszynski J, Taylor RE, Sackett DL, Schriemer DC. Huzil JT, et al. Among authors: freedman h. J Mol Biol. 2008 May 16;378(5):1016-30. doi: 10.1016/j.jmb.2008.03.026. Epub 2008 Mar 19. J Mol Biol. 2008. PMID: 18405918 Free PMC article.

4

Dynamics of RASSF1A/MOAP-1 association with death receptors.

Foley CJ, Freedman H, Choo SL, Onyskiw C, Fu NY, Yu VC, Tuszynski J, Pratt JC, Baksh S. Foley CJ, et al. Among authors: freedman h. Mol Cell Biol. 2008 Jul;28(14):4520-35. doi: 10.1128/MCB.02011-07. Epub 2008 May 12. Mol Cell Biol. 2008. PMID: 18474619 Free PMC article.

5

Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing.

Chen K, Huzil JT, Freedman H, Ramachandran P, Antoniou A, Tuszynski JA, Kurgan L. Chen K, et al. Among authors: freedman h. J Mol Graph Model. 2008 Nov;27(4):497-505. doi: 10.1016/j.jmgm.2008.09.001. Epub 2008 Sep 10. J Mol Graph Model. 2008. PMID: 18951052

6

Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity.

Freedman H, Huzil JT, Luchko T, Ludueña RF, Tuszynski JA. Freedman H, et al. J Chem Inf Model. 2009 Feb;49(2):424-36. doi: 10.1021/ci8003336. J Chem Inf Model. 2009. PMID: 19434843

7

Explicitly solvated ligand contribution to continuum solvation models for binding free energies: selectivity of theophylline binding to an RNA aptamer.

Freedman H, Huynh LP, Le L, Cheatham TE 3rd, Tuszynski JA, Truong TN. Freedman H, et al. J Phys Chem B. 2010 Feb 18;114(6):2227-37. doi: 10.1021/jp9059664. J Phys Chem B. 2010. PMID: 20099932

8

Microtubule ionic conduction and its implications for higher cognitive functions.

Craddock TJ, Tuszynski JA, Priel A, Freedman H. Craddock TJ, et al. Among authors: freedman h. J Integr Neurosci. 2010 Jun;9(2):103-22. doi: 10.1142/s0219635210002421. J Integr Neurosci. 2010. PMID: 20589950 Review.

9

Model of ionic currents through microtubule nanopores and the lumen.

Freedman H, Rezania V, Priel A, Carpenter E, Noskov SY, Tuszynski JA. Freedman H, et al. Phys Rev E Stat Nonlin Soft Matter Phys. 2010 May;81(5 Pt 1):051912. doi: 10.1103/PhysRevE.81.051912. Epub 2010 May 11. Phys Rev E Stat Nonlin Soft Matter Phys. 2010. PMID: 20866266

10

Molecular dynamics modeling of tubulin C-terminal tail interactions with the microtubule surface.

Freedman H, Luchko T, Luduena RF, Tuszynski JA. Freedman H, et al. Proteins. 2011 Oct;79(10):2968-82. doi: 10.1002/prot.23155. Epub 2011 Aug 26. Proteins. 2011. PMID: 21905119

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