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Sphingosine 1-phosphate receptor 1 inhibition induces a pro-apoptotic signaling cascade in T cells.
Dixit D, Hallisey VM, Zhu EYS, Okuniewska M, Cadwell K, Chipuk JE, Axelrad JE, Schwab SR. Dixit D, et al. Among authors: chipuk je. bioRxiv [Preprint]. 2023 Aug 22:2023.08.21.554104. doi: 10.1101/2023.08.21.554104. bioRxiv. 2023. Update in: J Clin Invest. 2024 Jan 9;134(4):e174984. doi: 10.1172/JCI174984 PMID: 37662380 Free PMC article. Updated. Preprint.
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1+ PD-1+ CD8 T cells.
Humblin E, Korpas I, Lu J, Filipescu D, van der Heide V, Goldstein S, Vaidya A, Soares-Schanoski A, Casati B, Selvan ME, Gümüş ZH, Wieland A, Corrado M, Cohen-Gould L, Bernstein E, Homann D, Chipuk J, Kamphorst AO. Humblin E, et al. Sci Immunol. 2023 Aug 4;8(86):eadg0878. doi: 10.1126/sciimmunol.adg0878. Epub 2023 Aug 25. Sci Immunol. 2023. PMID: 37624910 Free PMC article.
Mitochondrial dynamics as regulators of cancer biology.
Trotta AP, Chipuk JE. Trotta AP, et al. Among authors: chipuk je. Cell Mol Life Sci. 2017 Jun;74(11):1999-2017. doi: 10.1007/s00018-016-2451-3. Epub 2017 Jan 12. Cell Mol Life Sci. 2017. PMID: 28083595 Free PMC article. Review.
Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.
Lopez-Rivera E, Jayaraman P, Parikh F, Davies MA, Ekmekcioglu S, Izadmehr S, Milton DR, Chipuk JE, Grimm EA, Estrada Y, Aguirre-Ghiso J, Sikora AG. Lopez-Rivera E, et al. Among authors: chipuk je. Cancer Res. 2014 Feb 15;74(4):1067-78. doi: 10.1158/0008-5472.CAN-13-0588. Epub 2014 Jan 7. Cancer Res. 2014. PMID: 24398473 Free PMC article.
Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis.
Renault TT, Floros KV, Elkholi R, Corrigan KA, Kushnareva Y, Wieder SY, Lindtner C, Serasinghe MN, Asciolla JJ, Buettner C, Newmeyer DD, Chipuk JE. Renault TT, et al. Among authors: chipuk je. Mol Cell. 2015 Jan 8;57(1):69-82. doi: 10.1016/j.molcel.2014.10.028. Epub 2014 Dec 4. Mol Cell. 2015. PMID: 25482509 Free PMC article.
117 results