Lai Y - Search Results

1

Molecular Mechanisms of Fast Neurotransmitter Release.

Brunger AT, Choi UB, Lai Y, Leitz J, Zhou Q. Brunger AT, et al. Among authors: lai y. Annu Rev Biophys. 2018 May 20;47:469-497. doi: 10.1146/annurev-biophys-070816-034117. Annu Rev Biophys. 2018. PMID: 29792815 Free PMC article. Review.

2

Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms.

Lai Y, Diao J, Cipriano DJ, Zhang Y, Pfuetzner RA, Padolina MS, Brunger AT. Lai Y, et al. Elife. 2014 Aug 13;3:e03756. doi: 10.7554/eLife.03756. Elife. 2014. PMID: 25122624 Free PMC article.

3

N-terminal domain of complexin independently activates calcium-triggered fusion.

Lai Y, Choi UB, Zhang Y, Zhao M, Pfuetzner RA, Wang AL, Diao J, Brunger AT. Lai Y, et al. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4698-707. doi: 10.1073/pnas.1604348113. Epub 2016 Jul 21. Proc Natl Acad Sci U S A. 2016. PMID: 27444020 Free PMC article.

4

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.

Lai Y, Choi UB, Leitz J, Rhee HJ, Lee C, Altas B, Zhao M, Pfuetzner RA, Wang AL, Brose N, Rhee J, Brunger AT. Lai Y, et al. Neuron. 2017 Aug 2;95(3):591-607.e10. doi: 10.1016/j.neuron.2017.07.004. Neuron. 2017. PMID: 28772123 Free PMC article.

5

Ca²⁺-Triggered Synaptic Vesicle Fusion Initiated by Release of Inhibition.

Brunger AT, Leitz J, Zhou Q, Choi UB, Lai Y. Brunger AT, et al. Among authors: lai y. Trends Cell Biol. 2018 Aug;28(8):631-645. doi: 10.1016/j.tcb.2018.03.004. Epub 2018 Apr 26. Trends Cell Biol. 2018. PMID: 29706534 Free PMC article. Review.

6

The pre-synaptic fusion machinery.

Brunger AT, Choi UB, Lai Y, Leitz J, White KI, Zhou Q. Brunger AT, et al. Among authors: lai y. Curr Opin Struct Biol. 2019 Feb;54:179-188. doi: 10.1016/j.sbi.2019.03.007. Epub 2019 Apr 12. Curr Opin Struct Biol. 2019. PMID: 30986753 Free PMC article. Review.

7

ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.

Diao J, Liu R, Rong Y, Zhao M, Zhang J, Lai Y, Zhou Q, Wilz LM, Li J, Vivona S, Pfuetzner RA, Brunger AT, Zhong Q. Diao J, et al. Among authors: lai y. Nature. 2015 Apr 23;520(7548):563-6. doi: 10.1038/nature14147. Epub 2015 Feb 9. Nature. 2015. PMID: 25686604 Free PMC article.

8

Munc18a does not alter fusion rates mediated by neuronal SNAREs, synaptotagmin, and complexin.

Zhang Y, Diao J, Colbert KN, Lai Y, Pfuetzner RA, Padolina MS, Vivona S, Ressl S, Cipriano DJ, Choi UB, Shah N, Weis WI, Brunger AT. Zhang Y, et al. Among authors: lai y. J Biol Chem. 2015 Apr 17;290(16):10518-34. doi: 10.1074/jbc.M114.630772. Epub 2015 Feb 25. J Biol Chem. 2015. PMID: 25716318 Free PMC article.

9

Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis.

Zhou Q, Lai Y, Bacaj T, Zhao M, Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Brewster AS, Sauter NK, Cohen AE, Soltis SM, Alonso-Mori R, Chollet M, Lemke HT, Pfuetzner RA, Choi UB, Weis WI, Diao J, Südhof TC, Brunger AT. Zhou Q, et al. Among authors: lai y. Nature. 2015 Sep 3;525(7567):62-7. doi: 10.1038/nature14975. Epub 2015 Aug 17. Nature. 2015. PMID: 26280336 Free PMC article.

10

Complexin induces a conformational change at the membrane-proximal C-terminal end of the SNARE complex.

Choi UB, Zhao M, Zhang Y, Lai Y, Brunger AT. Choi UB, et al. Among authors: lai y. Elife. 2016 Jun 2;5:e16886. doi: 10.7554/eLife.16886. Elife. 2016. PMID: 27253060 Free PMC article.

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