Lefkowitz RJ - Search Results

1

Biased G Protein-Coupled Receptor Signaling: Changing the Paradigm of Drug Discovery.

Wisler JW, Rockman HA, Lefkowitz RJ. Wisler JW, et al. Among authors: lefkowitz rj. Circulation. 2018 May 29;137(22):2315-2317. doi: 10.1161/CIRCULATIONAHA.117.028194. Circulation. 2018. PMID: 29844068 Free PMC article. Review. No abstract available.

2

Cardiac muscarinic potassium channel activity is attenuated by inhibitors of G beta gamma.

Nair LA, Inglese J, Stoffel R, Koch WJ, Lefkowitz RJ, Kwatra MM, Grant AO. Nair LA, et al. Among authors: lefkowitz rj. Circ Res. 1995 May;76(5):832-8. doi: 10.1161/01.res.76.5.832. Circ Res. 1995. PMID: 7729000

3

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.

Koch WJ, Rockman HA, Samama P, Hamilton RA, Bond RA, Milano CA, Lefkowitz RJ. Koch WJ, et al. Among authors: lefkowitz rj. Science. 1995 Jun 2;268(5215):1350-3. doi: 10.1126/science.7761854. Science. 1995. PMID: 7761854

4

Marked enhancement in myocardial function resulting from overexpression of a human beta-adrenergic receptor gene.

Milano CA, Allen LF, Dolber PC, Johnson TD, Rockman HA, Bond RA, Lefkowitz RJ. Milano CA, et al. Among authors: lefkowitz rj. J Thorac Cardiovasc Surg. 1995 Feb;109(2):236-41. doi: 10.1016/s0022-5223(95)70384-5. J Thorac Cardiovasc Surg. 1995. PMID: 7853876 Free article.

5

Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy.

Milano CA, Dolber PC, Rockman HA, Bond RA, Venable ME, Allen LF, Lefkowitz RJ. Milano CA, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):10109-13. doi: 10.1073/pnas.91.21.10109. Proc Natl Acad Sci U S A. 1994. PMID: 7937846 Free PMC article.

6

Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor.

Milano CA, Allen LF, Rockman HA, Dolber PC, McMinn TR, Chien KR, Johnson TD, Bond RA, Lefkowitz RJ. Milano CA, et al. Among authors: lefkowitz rj. Science. 1994 Apr 22;264(5158):582-6. doi: 10.1126/science.8160017. Science. 1994. PMID: 8160017

7

Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein.

Rockman HA, Hamilton RA, Jones LR, Milano CA, Mao L, Lefkowitz RJ. Rockman HA, et al. Among authors: lefkowitz rj. J Clin Invest. 1996 Apr 1;97(7):1618-23. doi: 10.1172/JCI118587. J Clin Invest. 1996. PMID: 8601626 Free PMC article.

8

Transgenic manipulation of myocardial G protein-coupled receptors and receptor kinases.

Koch WJ, Milano CA, Lefkowitz RJ. Koch WJ, et al. Among authors: lefkowitz rj. Circ Res. 1996 Apr;78(4):511-6. doi: 10.1161/01.res.78.4.511. Circ Res. 1996. PMID: 8635207 Review. No abstract available.

9

Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice.

Rockman HA, Choi DJ, Rahman NU, Akhter SA, Lefkowitz RJ, Koch WJ. Rockman HA, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9954-9. doi: 10.1073/pnas.93.18.9954. Proc Natl Acad Sci U S A. 1996. PMID: 8790438 Free PMC article.

10

Myocardial beta-adrenergic receptor signaling in vivo: insights from transgenic mice.

Rockman HA, Koch WJ, Milano CA, Lefkowitz RJ. Rockman HA, et al. Among authors: lefkowitz rj. J Mol Med (Berl). 1996 Sep;74(9):489-95. doi: 10.1007/BF00204974. J Mol Med (Berl). 1996. PMID: 8892053 Review.

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