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Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma.
Noble RA, Bell N, Blair H, Sikka A, Thomas H, Phillips N, Nakjang S, Miwa S, Crossland R, Rand V, Televantou D, Long A, Keun HC, Bacon CM, Bomken S, Critchlow SE, Wedge SR. Noble RA, et al. Among authors: phillips n. Haematologica. 2017 Jul;102(7):1247-1257. doi: 10.3324/haematol.2016.163030. Epub 2017 Apr 6. Haematologica. 2017. PMID: 28385782 Free PMC article.
Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy.
Willoughby CE, Jiang Y, Thomas HD, Willmore E, Kyle S, Wittner A, Phillips N, Zhao Y, Tudhope SJ, Prendergast L, Junge G, Lourenco LM, Finlay MRV, Turner P, Munck JM, Griffin RJ, Rennison T, Pickles J, Cano C, Newell DR, Reeves HL, Ryan AJ, Wedge SR. Willoughby CE, et al. Among authors: phillips n. J Clin Invest. 2020 Jan 2;130(1):258-271. doi: 10.1172/JCI127483. J Clin Invest. 2020. PMID: 31581151 Free PMC article.
Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor.
Miller DC, Reuillon T, Molyneux L, Blackburn T, Cook SJ, Edwards N, Endicott JA, Golding BT, Griffin RJ, Hardcastle I, Harnor SJ, Heptinstall A, Lochhead P, Martin MP, Martin NC, Myers S, Newell DR, Noble RA, Phillips N, Rigoreau L, Thomas H, Tucker JA, Wang LZ, Waring MJ, Wong AC, Wedge SR, Noble MEM, Cano C. Miller DC, et al. Among authors: phillips n. J Med Chem. 2022 May 12;65(9):6513-6540. doi: 10.1021/acs.jmedchem.1c01756. Epub 2022 Apr 25. J Med Chem. 2022. PMID: 35468293 Free PMC article.
Targeting Cytotoxic Agents through EGFR-Mediated Covalent Binding and Release.
Morese PA, Anthony N, Bodnarchuk M, Jennings C, Martin MP, Noble RA, Phillips N, Thomas HD, Wang LZ, Lister A, Noble MEM, Ward RA, Wedge SR, Stewart HL, Waring MJ. Morese PA, et al. Among authors: phillips n. J Med Chem. 2023 Sep 14;66(17):12324-12341. doi: 10.1021/acs.jmedchem.3c00845. Epub 2023 Aug 30. J Med Chem. 2023. PMID: 37647129 Free PMC article.
The genomic and clinical consequences of replacing procarbazine with dacarbazine in escalated BEACOPP for Hodgkin lymphoma: a retrospective, observational study.
Santarsieri A, Mitchell E, Pham MH, Sanghvi R, Jablonski J, Lee-Six H, Sturgess K, Brice P, Menne TF, Osborne W, Creasey T, Ardeshna KM, Baxter J, Behan S, Bhuller K, Booth S, Chavda ND, Collins GP, Culligan DJ, Cwynarski K, Davies A, Downing A, Dutton D, Furtado M, Gallop-Evans E, Hodson A, Hopkins D, Hsu H, Iyengar S, Jones SG, Karanth M, Linton KM, Lomas OC, Martinez-Calle N, Mathur A, McKay P, Nagumantry SK, Phillips EH, Phillips N, Rudge JF, Shah NK, Stafford G, Sternberg A, Trickey R, Uttenthal BJ, Wetherall N, Zhang XY, McMillan AK, Coleman N, Stratton MR, Laurenti E, Borchmann P, Borchmann S, Campbell PJ, Rahbari R, Follows GA. Santarsieri A, et al. Among authors: phillips n. Lancet Oncol. 2024 Dec 11:S1470-2045(24)00598-9. doi: 10.1016/S1470-2045(24)00598-9. Online ahead of print. Lancet Oncol. 2024. PMID: 39674188 Free article.
Implementation of negative pressure for acute pediatric burns (INPREP): A stepped-wedge cluster randomized controlled trial protocol.
Holbert MD, Wood F, Holland AJA, Teague W, Kimble RM, Crellin D, Frear CC, Storey K, Phillips N, Singer Y, Dimanopoulos TA, Martin L, Cuttle L, Vagenas D, McPhail SM, Calleja P, Duff J, De Young A, Griffin BR. Holbert MD, et al. Among authors: phillips n. PLoS One. 2024 Dec 10;19(12):e0315278. doi: 10.1371/journal.pone.0315278. eCollection 2024. PLoS One. 2024. PMID: 39656723 Free PMC article.
Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA).
Chertkow H, Phillips N, Rockwood K, Anderson N, Andrew MK, Bartha R, Beaudoin C, Bélanger N, Bellec P, Belleville S, Bergman H, Best S, Bethell J, Bherer L, Black S, Borrie M, Camicioli R, Carrier J, Cashman N, Chan S, Crowshoe L, Cuello C, Cynader M, Dang-Vu T, Das S, Dixon RA, Ducharme S, Einstein G, Evans AC, Fahnestock M, Feldman H, Ferland G, Finger E, Fisk JD, Fogarty J, Fon E, Gan-Or Z, Gauthier S, Greenwood C, Henri-Bellemare C, Herrmann N, Hogan DB, Hsiung R, Itzhak I, Jacklin K, Lanctôt K, Lim A, MacKenzie I, Masellis M, Maxwell C, McAiney C, McGilton K, McLaurin J, Mihailidis A, Mohades Z, Montero-Odasso M, Morgan D, Naglie G, Nygaard H, O'Connell M, Petersen R, Pilon R, Rajah MN, Rapoport M, Roach P, Robillard JM, Rogaeva E, Rosa-Neto P, Rylett J, Sadavoy J, St George-Hyslop P, Seitz D, Smith E, Stefanovic B, Vedel I, Walker JD, Wellington C, Whitehead V, Wittich W. Chertkow H, et al. Among authors: phillips n. J Alzheimers Dis. 2024 Dec;102(3):535-561. doi: 10.1177/13872877241290990. Epub 2024 Dec 5. J Alzheimers Dis. 2024. PMID: 39636028 Review.
Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems.
Denoeud F, Godfroy O, Cruaud C, Heesch S, Nehr Z, Tadrent N, Couloux A, Brillet-Guéguen L, Delage L, Mckeown D, Motomura T, Sussfeld D, Fan X, Mazéas L, Terrapon N, Barrera-Redondo J, Petroll R, Reynes L, Choi SW, Jo J, Uthanumallian K, Bogaert K, Duc C, Ratchinski P, Lipinska A, Noel B, Murphy EA, Lohr M, Khatei A, Hamon-Giraud P, Vieira C, Avia K, Akerfors SS, Akita S, Badis Y, Barbeyron T, Belcour A, Berrabah W, Blanquart S, Bouguerba-Collin A, Bringloe T, Cattolico RA, Cormier A, Cruz de Carvalho H, Dallet R, De Clerck O, Debit A, Denis E, Destombe C, Dinatale E, Dittami S, Drula E, Faugeron S, Got J, Graf L, Groisillier A, Guillemin ML, Harms L, Hatchett WJ, Henrissat B, Hoarau G, Jollivet C, Jueterbock A, Kayal E, Knoll AH, Kogame K, Le Bars A, Leblanc C, Le Gall L, Ley R, Liu X, LoDuca ST, Lopez PJ, Lopez P, Manirakiza E, Massau K, Mauger S, Mest L, Michel G, Monteiro C, Nagasato C, Nègre D, Pelletier E, Phillips N, Potin P, Rensing SA, Rousselot E, Rousvoal S, Schroeder D, Scornet D, Siegel A, Tirichine L, Tonon T, Valentin K, Verbruggen H, Weinberger F, Wheeler G, Kawai H, Peters AF, Yoon HS, Hervé C, Ye N, Bapteste E, Valero M, Markov GV, Corre E, Coelho SM, Winck… See abstract for full author list ➔ Denoeud F, et al. Among authors: phillips n. Cell. 2024 Nov 27;187(24):6943-6965.e39. doi: 10.1016/j.cell.2024.10.049. Epub 2024 Nov 20. Cell. 2024. PMID: 39571576 Free article.
1,480 results