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The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle.
Neame S, Safory H, Radzishevsky I, Touitou A, Marchesani F, Marchetti M, Kellner S, Berlin S, Foltyn VN, Engelender S, Billard JM, Wolosker H. Neame S, et al. Among authors: wolosker h. Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20736-20742. doi: 10.1073/pnas.1909458116. Epub 2019 Sep 23. Proc Natl Acad Sci U S A. 2019. PMID: 31548413 Free PMC article.
ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d-serine and neurodevelopment.
Kaplan E, Zubedat S, Radzishevsky I, Valenta AC, Rechnitz O, Sason H, Sajrawi C, Bodner O, Konno K, Esaki K, Derdikman D, Yoshikawa T, Watanabe M, Kennedy RT, Billard JM, Avital A, Wolosker H. Kaplan E, et al. Among authors: wolosker h. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9628-9633. doi: 10.1073/pnas.1722677115. Epub 2018 Sep 5. Proc Natl Acad Sci U S A. 2018. PMID: 30185558 Free PMC article.
D-serine: physiology and pathology.
Radzishevsky I, Sason H, Wolosker H. Radzishevsky I, et al. Among authors: wolosker h. Curr Opin Clin Nutr Metab Care. 2013 Jan;16(1):72-5. doi: 10.1097/MCO.0b013e32835a3466. Curr Opin Clin Nutr Metab Care. 2013. PMID: 23041616 Review.
88 results