Parmar MK - Search Results

1

Rethinking non-inferiority: a practical trial design for optimising treatment duration.

Quartagno M, Walker AS, Carpenter JR, Phillips PP, Parmar MK. Quartagno M, et al. Among authors: parmar mk. Clin Trials. 2018 Oct;15(5):477-488. doi: 10.1177/1740774518778027. Epub 2018 Jun 5. Clin Trials. 2018. PMID: 29871495 Free PMC article.

2

Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial.

Sydes MR, Parmar MK, James ND, Clarke NW, Dearnaley DP, Mason MD, Morgan RC, Sanders K, Royston P. Sydes MR, et al. Among authors: parmar mk. Trials. 2009 Jun 11;10:39. doi: 10.1186/1745-6215-10-39. Trials. 2009. PMID: 19519885 Free PMC article. Clinical Trial.

3

Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit.

Royston P, Barthel FM, Parmar MK, Choodari-Oskooei B, Isham V. Royston P, et al. Among authors: parmar mk. Trials. 2011 Mar 18;12:81. doi: 10.1186/1745-6215-12-81. Trials. 2011. PMID: 21418571 Free PMC article.

4

Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial.

Sydes MR, Parmar MK, Mason MD, Clarke NW, Amos C, Anderson J, de Bono J, Dearnaley DP, Dwyer J, Green C, Jovic G, Ritchie AW, Russell JM, Sanders K, Thalmann G, James ND. Sydes MR, et al. Among authors: parmar mk. Trials. 2012 Sep 15;13:168. doi: 10.1186/1745-6215-13-168. Trials. 2012. PMID: 22978443 Free PMC article. Clinical Trial.

5

Impact of lack-of-benefit stopping rules on treatment effect estimates of two-arm multi-stage (TAMS) trials with time to event outcome.

Choodari-Oskooei B, Parmar MK, Royston P, Bowden J. Choodari-Oskooei B, et al. Among authors: parmar mk. Trials. 2013 Jan 23;14:23. doi: 10.1186/1745-6215-14-23. Trials. 2013. PMID: 23343147 Free PMC article.

6

A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis.

Bratton DJ, Phillips PP, Parmar MK. Bratton DJ, et al. Among authors: parmar mk. BMC Med Res Methodol. 2013 Nov 14;13:139. doi: 10.1186/1471-2288-13-139. BMC Med Res Methodol. 2013. PMID: 24229079 Free PMC article.

7

Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome.

Royston P, Parmar MK. Royston P, et al. Among authors: parmar mk. BMC Med Res Methodol. 2013 Dec 7;13:152. doi: 10.1186/1471-2288-13-152. BMC Med Res Methodol. 2013. PMID: 24314264 Free PMC article.

8

More multiarm randomised trials of superiority are needed.

Parmar MK, Carpenter J, Sydes MR. Parmar MK, et al. Lancet. 2014 Jul 26;384(9940):283-4. doi: 10.1016/S0140-6736(14)61122-3. Lancet. 2014. PMID: 25066148 No abstract available.

9

An approach to trial design and analysis in the era of non-proportional hazards of the treatment effect.

Royston P, Parmar MK. Royston P, et al. Among authors: parmar mk. Trials. 2014 Aug 7;15:314. doi: 10.1186/1745-6215-15-314. Trials. 2014. PMID: 25098243 Free PMC article.

10

Optimisation of pharmacy content in clinical cancer research protocols: Experience of the United Kingdom Chemotherapy and Pharmacy Advisory Service.

Debruyne PR, Johnson PJ, Pottel L, Daniels S, Greer R, Hodgkinson E, Kelly S, Lycke M, Samol J, Mason J, Kimber D, Loucaides E, Parmar MK, Harvey S; NIHR CRN – CPAS. Debruyne PR, et al. Among authors: parmar mk. Clin Trials. 2015 Jun;12(3):257-64. doi: 10.1177/1740774515569610. Epub 2015 Feb 4. Clin Trials. 2015. PMID: 25652529

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