Witztum JL - Search Results

1

Oxidation-specific epitopes restrain bone formation.

Ambrogini E, Que X, Wang S, Yamaguchi F, Weinstein RS, Tsimikas S, Manolagas SC, Witztum JL, Jilka RL. Ambrogini E, et al. Among authors: witztum jl. Nat Commun. 2018 Jun 6;9(1):2193. doi: 10.1038/s41467-018-04047-5. Nat Commun. 2018. PMID: 29875355 Free PMC article.

2

Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

Palinski W, Ylä-Herttuala S, Rosenfeld ME, Butler SW, Socher SA, Parthasarathy S, Curtiss LK, Witztum JL. Palinski W, et al. Among authors: witztum jl. Arteriosclerosis. 1990 May-Jun;10(3):325-35. doi: 10.1161/01.atv.10.3.325. Arteriosclerosis. 1990. PMID: 1693068

3

ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

Palinski W, Ord VA, Plump AS, Breslow JL, Steinberg D, Witztum JL. Palinski W, et al. Among authors: witztum jl. Arterioscler Thromb. 1994 Apr;14(4):605-16. doi: 10.1161/01.atv.14.4.605. Arterioscler Thromb. 1994. PMID: 7511933

4

Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo.

Tsimikas S, Palinski W, Halpern SE, Yeung DW, Curtiss LK, Witztum JL. Tsimikas S, et al. Among authors: witztum jl. J Nucl Cardiol. 1999 Jan-Feb;6(1 Pt 1):41-53. doi: 10.1016/s1071-3581(99)90064-8. J Nucl Cardiol. 1999. PMID: 10070840

5

Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition.

Chang MK, Bergmark C, Laurila A, Hörkkö S, Han KH, Friedman P, Dennis EA, Witztum JL. Chang MK, et al. Among authors: witztum jl. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6353-8. doi: 10.1073/pnas.96.11.6353. Proc Natl Acad Sci U S A. 1999. PMID: 10339591 Free PMC article.

6

In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regression.

Tsimikas S, Shortal BP, Witztum JL, Palinski W. Tsimikas S, et al. Among authors: witztum jl. Arterioscler Thromb Vasc Biol. 2000 Mar;20(3):689-97. doi: 10.1161/01.atv.20.3.689. Arterioscler Thromb Vasc Biol. 2000. PMID: 10712392

7

Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice.

Tsimikas S, Palinski W, Witztum JL. Tsimikas S, et al. Among authors: witztum jl. Arterioscler Thromb Vasc Biol. 2001 Jan;21(1):95-100. doi: 10.1161/01.atv.21.1.95. Arterioscler Thromb Vasc Biol. 2001. PMID: 11145939

8

Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk.

Tsimikas S, Witztum JL. Tsimikas S, et al. Among authors: witztum jl. Circulation. 2001 Apr 17;103(15):1930-2. doi: 10.1161/01.cir.103.15.1930. Circulation. 2001. PMID: 11306518 No abstract available.

9

Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo.

Shaw PX, Hörkkö S, Tsimikas S, Chang MK, Palinski W, Silverman GJ, Chen PP, Witztum JL. Shaw PX, et al. Among authors: witztum jl. Arterioscler Thromb Vasc Biol. 2001 Aug;21(8):1333-9. doi: 10.1161/hq0801.093587. Arterioscler Thromb Vasc Biol. 2001. PMID: 11498462

10

Shifting the diagnosis and treatment of atherosclerosis to children and young adults: a new paradigm for the 21st century.

Tsimikas S, Witztum JL. Tsimikas S, et al. Among authors: witztum jl. J Am Coll Cardiol. 2002 Dec 18;40(12):2122-4. doi: 10.1016/s0735-1097(02)02599-8. J Am Coll Cardiol. 2002. PMID: 12505223 Free article. No abstract available.

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