Leonard A - Search Results

1

Stem cell transplantation in sickle cell disease: therapeutic potential and challenges faced.

Leonard A, Tisdale JF. Leonard A, et al. Expert Rev Hematol. 2018 Jul;11(7):547-565. doi: 10.1080/17474086.2018.1486703. Epub 2018 Jun 20. Expert Rev Hematol. 2018. PMID: 29883237 Free PMC article. Review.

2

CRISPR/Cas9 for Sickle Cell Disease: Applications, Future Possibilities, and Challenges.

Demirci S, Leonard A, Haro-Mora JJ, Uchida N, Tisdale JF. Demirci S, et al. Among authors: leonard a. Adv Exp Med Biol. 2019;1144:37-52. doi: 10.1007/5584_2018_331. Adv Exp Med Biol. 2019. PMID: 30715679 Review.

3

High-Efficiency Lentiviral Transduction of Human CD34⁺ Cells in High-Density Culture with Poloxamer and Prostaglandin E2.

Uchida N, Nassehi T, Drysdale CM, Gamer J, Yapundich M, Demirci S, Haro-Mora JJ, Leonard A, Hsieh MM, Tisdale JF. Uchida N, et al. Among authors: leonard a. Mol Ther Methods Clin Dev. 2019 Jan 25;13:187-196. doi: 10.1016/j.omtm.2019.01.005. eCollection 2019 Jun 14. Mol Ther Methods Clin Dev. 2019. PMID: 30788387 Free PMC article.

4

Bone marrow characterization in sickle cell disease: inflammation and stress erythropoiesis lead to suboptimal CD34 recovery.

Leonard A, Bonifacino A, Dominical VM, Luo M, Haro-Mora JJ, Demirci S, Uchida N, Pierciey FJ Jr, Tisdale JF. Leonard A, et al. Br J Haematol. 2019 Jul;186(2):286-299. doi: 10.1111/bjh.15902. Epub 2019 Apr 10. Br J Haematol. 2019. PMID: 30972754 Free PMC article.

5

Low-Dose Busulfan Reduces Human CD34⁺ Cell Doses Required for Engraftment in c-kit Mutant Immunodeficient Mice.

Leonard A, Yapundich M, Nassehi T, Gamer J, Drysdale CM, Haro-Mora JJ, Demirci S, Hsieh MM, Uchida N, Tisdale JF. Leonard A, et al. Mol Ther Methods Clin Dev. 2019 Nov 11;15:430-437. doi: 10.1016/j.omtm.2019.10.017. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31890735 Free PMC article.

6

Curative options for sickle cell disease: haploidentical stem cell transplantation or gene therapy?

Leonard A, Tisdale J, Abraham A. Leonard A, et al. Br J Haematol. 2020 May;189(3):408-423. doi: 10.1111/bjh.16437. Epub 2020 Feb 7. Br J Haematol. 2020. PMID: 32034776 Free article. Review.

7

[No title available]

[No authors listed] [No authors listed] PMID: 32054658

8

Genome editing strategies for fetal hemoglobin induction in beta-hemoglobinopathies.

Demirci S, Leonard A, Tisdale JF. Demirci S, et al. Among authors: leonard a. Hum Mol Genet. 2020 Sep 30;29(R1):R100-R106. doi: 10.1093/hmg/ddaa088. Hum Mol Genet. 2020. PMID: 32406490 Free PMC article. Review.

9

Hematopoietic stem cells from pluripotent stem cells: Clinical potential, challenges, and future perspectives.

Demirci S, Leonard A, Tisdale JF. Demirci S, et al. Among authors: leonard a. Stem Cells Transl Med. 2020 Dec;9(12):1549-1557. doi: 10.1002/sctm.20-0247. Epub 2020 Jul 29. Stem Cells Transl Med. 2020. PMID: 32725882 Free PMC article. Review.

10

BCL11A enhancer-edited hematopoietic stem cells persist in rhesus monkeys without toxicity.

Demirci S, Zeng J, Wu Y, Uchida N, Shen AH, Pellin D, Gamer J, Yapundich M, Drysdale C, Bonanno J, Bonifacino AC, Krouse AE, Linde NS, Engels T, Donahue RE, Haro-Mora JJ, Leonard A, Nassehi T, Luk K, Porter SN, Lazzarotto CR, Tsai SQ, Weiss MJ, Pruett-Miller SM, Wolfe SA, Bauer DE, Tisdale JF. Demirci S, et al. Among authors: leonard a. J Clin Invest. 2020 Dec 1;130(12):6677-6687. doi: 10.1172/JCI140189. J Clin Invest. 2020. PMID: 32897878 Free PMC article.

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