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Page 1
Identification of a novel tetrameric structure for human apolipoprotein-D.
Kielkopf CS, Low JKK, Mok YF, Bhatia S, Palasovski T, Oakley AJ, Whitten AE, Garner B, Brown SHJ. Kielkopf CS, et al. Among authors: whitten ae. J Struct Biol. 2018 Sep;203(3):205-218. doi: 10.1016/j.jsb.2018.05.012. Epub 2018 Jun 6. J Struct Biol. 2018. PMID: 29885491
Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change.
Whitten AE, Smith BJ, Menting JG, Margetts MB, McKern NM, Lovrecz GO, Adams TE, Richards K, Bentley JD, Trewhella J, Ward CW, Lawrence MC. Whitten AE, et al. J Mol Biol. 2009 Dec 18;394(5):878-92. doi: 10.1016/j.jmb.2009.10.011. Epub 2009 Oct 14. J Mol Biol. 2009. PMID: 19835884
A novel structure of an antikinase and its inhibitor.
Jacques DA, Langley DB, Hynson RM, Whitten AE, Kwan A, Guss JM, Trewhella J. Jacques DA, et al. Among authors: whitten ae. J Mol Biol. 2011 Jan 7;405(1):214-26. doi: 10.1016/j.jmb.2010.10.047. Epub 2010 Nov 2. J Mol Biol. 2011. PMID: 21050859
SNARE-ing the structures of Sec1/Munc18 proteins.
Archbold JK, Whitten AE, Hu SH, Collins BM, Martin JL. Archbold JK, et al. Among authors: whitten ae. Curr Opin Struct Biol. 2014 Dec;29:44-51. doi: 10.1016/j.sbi.2014.09.003. Epub 2014 Oct 2. Curr Opin Struct Biol. 2014. PMID: 25282382 Review.
Domain-swap polymerization drives the self-assembly of the bacterial flagellar motor.
Baker MA, Hynson RM, Ganuelas LA, Mohammadi NS, Liew CW, Rey AA, Duff AP, Whitten AE, Jeffries CM, Delalez NJ, Morimoto YV, Stock D, Armitage JP, Turberfield AJ, Namba K, Berry RM, Lee LK. Baker MA, et al. Among authors: whitten ae. Nat Struct Mol Biol. 2016 Mar;23(3):197-203. doi: 10.1038/nsmb.3172. Epub 2016 Feb 8. Nat Struct Mol Biol. 2016. PMID: 26854663
2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update.
Trewhella J, Duff AP, Durand D, Gabel F, Guss JM, Hendrickson WA, Hura GL, Jacques DA, Kirby NM, Kwan AH, Pérez J, Pollack L, Ryan TM, Sali A, Schneidman-Duhovny D, Schwede T, Svergun DI, Sugiyama M, Tainer JA, Vachette P, Westbrook J, Whitten AE. Trewhella J, et al. Among authors: whitten ae. Acta Crystallogr D Struct Biol. 2017 Sep 1;73(Pt 9):710-728. doi: 10.1107/S2059798317011597. Epub 2017 Aug 18. Acta Crystallogr D Struct Biol. 2017. PMID: 28876235 Free PMC article.
Production, biophysical characterization and initial crystallization studies of the N- and C-terminal domains of DsbD, an essential enzyme in Neisseria meningitidis.
Smith RP, Whitten AE, Paxman JJ, Kahler CM, Scanlon MJ, Heras B. Smith RP, et al. Among authors: whitten ae. Acta Crystallogr F Struct Biol Commun. 2018 Jan 1;74(Pt 1):31-38. doi: 10.1107/S2053230X17017800. Epub 2018 Jan 1. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29372905 Free PMC article.
Engineered variants provide new insight into the structural properties important for activity of the highly dynamic, trimeric protein disulfide isomerase ScsC from Proteus mirabilis.
Furlong EJ, Kurth F, Premkumar L, Whitten AE, Martin JL. Furlong EJ, et al. Among authors: whitten ae. Acta Crystallogr D Struct Biol. 2019 Mar 1;75(Pt 3):296-307. doi: 10.1107/S2059798319000081. Epub 2019 Feb 26. Acta Crystallogr D Struct Biol. 2019. PMID: 30950400 Free PMC article.
The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity.
Petit GA, Hong Y, Djoko KY, Whitten AE, Furlong EJ, McCoy AJ, Gulbis JM, Totsika M, Martin JL, Halili MA. Petit GA, et al. Among authors: whitten ae. Acta Crystallogr D Struct Biol. 2022 Mar 1;78(Pt 3):337-352. doi: 10.1107/S2059798322000729. Epub 2022 Feb 21. Acta Crystallogr D Struct Biol. 2022. PMID: 35234148 Free PMC article.
72 results