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The human heart contains distinct macrophage subsets with divergent origins and functions.
Bajpai G, Schneider C, Wong N, Bredemeyer A, Hulsmans M, Nahrendorf M, Epelman S, Kreisel D, Liu Y, Itoh A, Shankar TS, Selzman CH, Drakos SG, Lavine KJ. Bajpai G, et al. Among authors: lavine kj. Nat Med. 2018 Aug;24(8):1234-1245. doi: 10.1038/s41591-018-0059-x. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892064 Free PMC article.
Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility.
Garg A, Jansen S, Zhang R, Lavine KJ, Greenberg MJ. Garg A, et al. Among authors: lavine kj. bioRxiv [Preprint]. 2024 Mar 12:2024.03.10.583979. doi: 10.1101/2024.03.10.583979. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2024 Nov 12;121(46):e2405020121. doi: 10.1073/pnas.2405020121 PMID: 38559046 Free PMC article. Updated. Preprint.
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation.
Epelman S, Lavine KJ, Beaudin AE, Sojka DK, Carrero JA, Calderon B, Brija T, Gautier EL, Ivanov S, Satpathy AT, Schilling JD, Schwendener R, Sergin I, Razani B, Forsberg EC, Yokoyama WM, Unanue ER, Colonna M, Randolph GJ, Mann DL. Epelman S, et al. Among authors: lavine kj. Immunity. 2014 Jan 16;40(1):91-104. doi: 10.1016/j.immuni.2013.11.019. Immunity. 2014. PMID: 24439267 Free PMC article.
Origin and functions of tissue macrophages.
Epelman S, Lavine KJ, Randolph GJ. Epelman S, et al. Among authors: lavine kj. Immunity. 2014 Jul 17;41(1):21-35. doi: 10.1016/j.immuni.2014.06.013. Immunity. 2014. PMID: 25035951 Free PMC article. Review.
Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
Sager HB, Hulsmans M, Lavine KJ, Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M. Sager HB, et al. Among authors: lavine kj. Circ Res. 2016 Sep 16;119(7):853-64. doi: 10.1161/CIRCRESAHA.116.309001. Epub 2016 Jul 21. Circ Res. 2016. PMID: 27444755 Free PMC article.
147 results