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Page 1
Myeloid Kdm6b deficiency results in advanced atherosclerosis.
Neele AE, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Prange KHM, Chen HJ, Van den Bossche J, van Roomen CPPA, Shami A, Levels JHM, Kroon J, Lucas T, Dimmeler S, Lutgens E, de Winther MPJ. Neele AE, et al. Among authors: kroon j. Atherosclerosis. 2018 Aug;275:156-165. doi: 10.1016/j.atherosclerosis.2018.05.052. Epub 2018 Jun 1. Atherosclerosis. 2018. PMID: 29908485 Free article.
Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans.
van der Valk FM, Bekkering S, Kroon J, Yeang C, Van den Bossche J, van Buul JD, Ravandi A, Nederveen AJ, Verberne HJ, Scipione C, Nieuwdorp M, Joosten LA, Netea MG, Koschinsky ML, Witztum JL, Tsimikas S, Riksen NP, Stroes ES. van der Valk FM, et al. Among authors: kroon j. Circulation. 2016 Aug 23;134(8):611-24. doi: 10.1161/CIRCULATIONAHA.116.020838. Epub 2016 Aug 5. Circulation. 2016. PMID: 27496857 Free PMC article. Clinical Trial.
Metabolism: The road to inflammation and atherosclerosis.
Ali L, Schnitzler JG, Kroon J. Ali L, et al. Among authors: kroon j. Curr Opin Lipidol. 2018 Dec;29(6):474-480. doi: 10.1097/MOL.0000000000000550. Curr Opin Lipidol. 2018. PMID: 30234554 Review.
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates.
Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R. Lameijer M, et al. Among authors: kroon j. Nat Biomed Eng. 2018 May;2(5):279-292. doi: 10.1038/s41551-018-0221-2. Epub 2018 Apr 16. Nat Biomed Eng. 2018. PMID: 30936448 Free PMC article.
N-Glycosylation Defects in Humans Lower Low-Density Lipoprotein Cholesterol Through Increased Low-Density Lipoprotein Receptor Expression.
van den Boogert MAW, Larsen LE, Ali L, Kuil SD, Chong PLW, Loregger A, Kroon J, Schnitzler JG, Schimmel AWM, Peter J, Levels JHM, Steenbergen G, Morava E, Dallinga-Thie GM, Wevers RA, Kuivenhoven JA, Hand NJ, Zelcer N, Rader DJ, Stroes ESG, Lefeber DJ, Holleboom AG. van den Boogert MAW, et al. Among authors: kroon j. Circulation. 2019 Jul 23;140(4):280-292. doi: 10.1161/CIRCULATIONAHA.118.036484. Epub 2019 May 23. Circulation. 2019. PMID: 31117816
Salt increases monocyte CCR2 expression and inflammatory responses in humans.
Wenstedt EF, Verberk SG, Kroon J, Neele AE, Baardman J, Claessen N, Pasaoglu ÖT, Rademaker E, Schrooten EM, Wouda RD, de Winther MP, Aten J, Vogt L, Van den Bossche J. Wenstedt EF, et al. Among authors: kroon j. JCI Insight. 2019 Nov 1;4(21):e130508. doi: 10.1172/jci.insight.130508. JCI Insight. 2019. PMID: 31672939 Free PMC article. Clinical Trial.
Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial.
de Groot PF, Nikolic T, Imangaliyev S, Bekkering S, Duinkerken G, Keij FM, Herrema H, Winkelmeijer M, Kroon J, Levin E, Hutten B, Kemper EM, Simsek S, Levels JHM, van Hoorn FA, Bindraban R, Berkvens A, Dallinga-Thie GM, Davids M, Holleman F, Hoekstra JBL, Stroes ESG, Netea M, van Raalte DH, Roep BO, Nieuwdorp M. de Groot PF, et al. Among authors: kroon j. Diabetologia. 2020 Mar;63(3):597-610. doi: 10.1007/s00125-019-05073-8. Epub 2020 Jan 8. Diabetologia. 2020. PMID: 31915895 Clinical Trial.
Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation.
Schnitzler JG, Hoogeveen RM, Ali L, Prange KHM, Waissi F, van Weeghel M, Bachmann JC, Versloot M, Borrelli MJ, Yeang C, De Kleijn DPV, Houtkooper RH, Koschinsky ML, de Winther MPJ, Groen AK, Witztum JL, Tsimikas S, Stroes ESG, Kroon J. Schnitzler JG, et al. Among authors: kroon j. Circ Res. 2020 May 8;126(10):1346-1359. doi: 10.1161/CIRCRESAHA.119.316206. Epub 2020 Mar 12. Circ Res. 2020. PMID: 32160811 Free PMC article.
Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a).
Stiekema LCA, Prange KHM, Hoogeveen RM, Verweij SL, Kroon J, Schnitzler JG, Dzobo KE, Cupido AJ, Tsimikas S, Stroes ESG, de Winther MPJ, Bahjat M. Stiekema LCA, et al. Among authors: kroon j. Eur Heart J. 2020 Jun 21;41(24):2262-2271. doi: 10.1093/eurheartj/ehaa171. Eur Heart J. 2020. PMID: 32268367 Free PMC article.
331 results