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Discovery of the Human Immunodeficiency Virus Type 1 (HIV-1) Attachment Inhibitor Temsavir and Its Phosphonooxymethyl Prodrug Fostemsavir.
Wang T, Ueda Y, Zhang Z, Yin Z, Matiskella J, Pearce BC, Yang Z, Zheng M, Parker DD, Yamanaka GA, Gong YF, Ho HT, Colonno RJ, Langley DR, Lin PF, Meanwell NA, Kadow JF. Wang T, et al. Among authors: kadow jf. J Med Chem. 2018 Jul 26;61(14):6308-6327. doi: 10.1021/acs.jmedchem.8b00759. Epub 2018 Jul 13. J Med Chem. 2018. PMID: 29920093
Inhibitors of the entry of HIV into host cells.
Meanwell NA, Kadow JF. Meanwell NA, et al. Among authors: kadow jf. Curr Opin Drug Discov Devel. 2003 Jul;6(4):451-61. Curr Opin Drug Discov Devel. 2003. PMID: 12951808 Review.
Developments in antiviral drug design, discovery and development in 2004.
Meanwell NA, Belema M, Carini DJ, D'Andrea SV, Kadow JF, Krystal M, Naidu BN, Regueiro-Ren A, Scola PM, Sit SY, Walker MA, Wang T, Yeung KS. Meanwell NA, et al. Among authors: kadow jf. Curr Drug Targets Infect Disord. 2005 Dec;5(4):307-400. doi: 10.2174/156800505774912893. Curr Drug Targets Infect Disord. 2005. PMID: 16535860 Review.
Envelope conformational changes induced by human immunodeficiency virus type 1 attachment inhibitors prevent CD4 binding and downstream entry events.
Ho HT, Fan L, Nowicka-Sans B, McAuliffe B, Li CB, Yamanaka G, Zhou N, Fang H, Dicker I, Dalterio R, Gong YF, Wang T, Yin Z, Ueda Y, Matiskella J, Kadow J, Clapham P, Robinson J, Colonno R, Lin PF. Ho HT, et al. J Virol. 2006 Apr;80(8):4017-25. doi: 10.1128/JVI.80.8.4017-4025.2006. J Virol. 2006. PMID: 16571818 Free PMC article.
78 results