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In utero nanoparticle delivery for site-specific genome editing.
Ricciardi AS, Bahal R, Farrelly JS, Quijano E, Bianchi AH, Luks VL, Putman R, López-Giráldez F, Coşkun S, Song E, Liu Y, Hsieh WC, Ly DH, Stitelman DH, Glazer PM, Saltzman WM. Ricciardi AS, et al. Among authors: luks vl. Nat Commun. 2018 Jun 26;9(1):2481. doi: 10.1038/s41467-018-04894-2. Nat Commun. 2018. PMID: 29946143 Free PMC article.
CT imaging-derived phenotypes for abdominal muscle and their association with age and sex in a medical biobank.
Vu PT, Chahine C, Chatterjee N, MacLean MT, Swago S, Bhattaru A, Thompson EW, Ikhlas A, Oteng E, Davidson L, Tran R, Hazim M, Raghupathy P, Verma A, Duda J, Gee J, Luks V, Gershuni V, Wu G, Rader D, Sagreiya H, Witschey WR; Penn Medicine Biobank. Vu PT, et al. Sci Rep. 2024 Jun 26;14(1):14807. doi: 10.1038/s41598-024-64603-6. Sci Rep. 2024. PMID: 38926479 Free PMC article.
In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells.
Palanki R, Riley JS, Bose SK, Luks V, Dave A, Kus N, White BM, Ricciardi AS, Swingle KL, Xue L, Sung D, Thatte AS, Safford HC, Chaluvadi VS, Carpenter M, Han EL, Maganti R, Hamilton AG, Mrksich K, Billingsley MB, Zoltick PW, Alameh MG, Weissman D, Mitchell MJ, Peranteau WH. Palanki R, et al. Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2400783121. doi: 10.1073/pnas.2400783121. Epub 2024 Jul 30. Proc Natl Acad Sci U S A. 2024. PMID: 39078677
Systemic in utero gene editing as a treatment for cystic fibrosis.
Ricciardi AS, Barone C, Putman R, Quijano E, Gupta A, Nguyen R, Mandl H, Piotrowski-Daspit AS, Lopez-Giraldez F, Luks V, Freedman-Weiss MR, Farrelly J, Ahle S, Glazer PM, Saltzman WM, Stitelman DH, Egan ME. Ricciardi AS, et al. bioRxiv [Preprint]. 2024 Sep 8:2024.09.04.611031. doi: 10.1101/2024.09.04.611031. bioRxiv. 2024. PMID: 39282330 Free PMC article. Preprint.
Molecular and Cellular In Utero Therapy.
Berkowitz CL, Luks VL, Puc M, Peranteau WH. Berkowitz CL, et al. Among authors: luks vl. Clin Perinatol. 2022 Dec;49(4):811-820. doi: 10.1016/j.clp.2022.06.005. Epub 2022 Oct 9. Clin Perinatol. 2022. PMID: 36328600 Review.
Preexisting maternal immunity to AAV but not Cas9 impairs in utero gene editing in mice.
Riley JS, Luks VL, Berkowitz CL, Dumitru AM, Kus NJ, Dave A, Menon P, De Paepe ME, Jain R, Li L, Dugoff L, Teefey CP, Alameh MG, Zoltick PW, Peranteau WH. Riley JS, et al. Among authors: luks vl. J Clin Invest. 2024 May 9;134(12):e179848. doi: 10.1172/JCI179848. J Clin Invest. 2024. PMID: 38950310 Free PMC article.
28 results