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Page 1
Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH. Gruszczyk J, et al. Among authors: pearson rd. Nature. 2018 Jul;559(7712):135-139. doi: 10.1038/s41586-018-0249-1. Epub 2018 Jun 27. Nature. 2018. PMID: 29950717
Genomic analysis of local variation and recent evolution in Plasmodium vivax.
Pearson RD, Amato R, Auburn S, Miotto O, Almagro-Garcia J, Amaratunga C, Suon S, Mao S, Noviyanti R, Trimarsanto H, Marfurt J, Anstey NM, William T, Boni MF, Dolecek C, Hien TT, White NJ, Michon P, Siba P, Tavul L, Harrison G, Barry A, Mueller I, Ferreira MU, Karunaweera N, Randrianarivelojosia M, Gao Q, Hubbart C, Hart L, Jeffery B, Drury E, Mead D, Kekre M, Campino S, Manske M, Cornelius VJ, MacInnis B, Rockett KA, Miles A, Rayner JC, Fairhurst RM, Nosten F, Price RN, Kwiatkowski DP. Pearson RD, et al. Nat Genet. 2016 Aug;48(8):959-964. doi: 10.1038/ng.3599. Epub 2016 Jun 27. Nat Genet. 2016. PMID: 27348299 Free PMC article.
Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax.
Gruszczyk J, Kanjee U, Chan LJ, Menant S, Malleret B, Lim NTY, Schmidt CQ, Mok YF, Lin KM, Pearson RD, Rangel G, Smith BJ, Call MJ, Weekes MP, Griffin MDW, Murphy JM, Abraham J, Sriprawat K, Menezes MJ, Ferreira MU, Russell B, Renia L, Duraisingh MT, Tham WH. Gruszczyk J, et al. Among authors: pearson rd. Science. 2018 Jan 5;359(6371):48-55. doi: 10.1126/science.aan1078. Science. 2018. PMID: 29302006 Free PMC article.
Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics.
Auburn S, Benavente ED, Miotto O, Pearson RD, Amato R, Grigg MJ, Barber BE, William T, Handayuni I, Marfurt J, Trimarsanto H, Noviyanti R, Sriprawat K, Nosten F, Campino S, Clark TG, Anstey NM, Kwiatkowski DP, Price RN. Auburn S, et al. Among authors: pearson rd. Nat Commun. 2018 Jul 3;9(1):2585. doi: 10.1038/s41467-018-04965-4. Nat Commun. 2018. PMID: 29968722 Free PMC article.
Genomic Analysis of Plasmodium vivax in Southern Ethiopia Reveals Selective Pressures in Multiple Parasite Mechanisms.
Auburn S, Getachew S, Pearson RD, Amato R, Miotto O, Trimarsanto H, Zhu SJ, Rumaseb A, Marfurt J, Noviyanti R, Grigg MJ, Barber B, William T, Goncalves SM, Drury E, Sriprawat K, Anstey NM, Nosten F, Petros B, Aseffa A, McVean G, Kwiatkowski DP, Price RN. Auburn S, et al. Among authors: pearson rd. J Infect Dis. 2019 Oct 22;220(11):1738-1749. doi: 10.1093/infdis/jiz016. J Infect Dis. 2019. PMID: 30668735 Free PMC article.
Genetic diversity and neutral selection in Plasmodium vivax erythrocyte binding protein correlates with patient antigenicity.
Han JH, Cho JS, Ong JJY, Park JH, Nyunt MH, Sutanto E, Trimarsanto H, Petros B, Aseffa A, Getachew S, Sriprawat K, Anstey NM, Grigg MJ, Barber BE, William T, Qi G, Liu Y, Pearson RD, Auburn S, Price RN, Nosten F, Rénia L, Russell B, Han ET. Han JH, et al. Among authors: pearson rd. PLoS Negl Trop Dis. 2020 Jul 9;14(7):e0008202. doi: 10.1371/journal.pntd.0008202. eCollection 2020 Jul. PLoS Negl Trop Dis. 2020. PMID: 32645098 Free PMC article.
Malaria protection due to sickle haemoglobin depends on parasite genotype.
Band G, Leffler EM, Jallow M, Sisay-Joof F, Ndila CM, Macharia AW, Hubbart C, Jeffreys AE, Rowlands K, Nguyen T, Gonçalves S, Ariani CV, Stalker J, Pearson RD, Amato R, Drury E, Sirugo G, d'Alessandro U, Bojang KA, Marsh K, Peshu N, Saelens JW, Diakité M, Taylor SM, Conway DJ, Williams TN, Rockett KA, Kwiatkowski DP. Band G, et al. Among authors: pearson rd. Nature. 2022 Feb;602(7895):106-111. doi: 10.1038/s41586-021-04288-3. Epub 2021 Dec 9. Nature. 2022. PMID: 34883497 Free PMC article.
Geographical distribution and genetic diversity of Plasmodium vivax reticulocyte binding protein 1a correlates with patient antigenicity.
Park JH, Kim MH, Sutanto E, Na SW, Kim MJ, Yeom JS, Nyunt MH, Abbas Elfaki MM, Abdel Hamid MM, Cha SH, Alemu SG, Sriprawat K, Anstey NM, Grigg MJ, Barber BE, William T, Gao Q, Liu Y, Pearson RD, Price RN, Nosten F, Yoon SI, No JH, Han ET, Auburn S, Russell B, Han JH. Park JH, et al. Among authors: pearson rd. PLoS Negl Trop Dis. 2022 Jun 23;16(6):e0010492. doi: 10.1371/journal.pntd.0010492. eCollection 2022 Jun. PLoS Negl Trop Dis. 2022. PMID: 35737709 Free PMC article.
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum.
Kümpornsin K, Kochakarn T, Yeo T, Okombo J, Luth MR, Hoshizaki J, Rawat M, Pearson RD, Schindler KA, Mok S, Park H, Uhlemann AC, Jana GP, Maity BC, Laleu B, Chenu E, Duffy J, Moliner Cubel S, Franco V, Gomez-Lorenzo MG, Gamo FJ, Winzeler EA, Fidock DA, Chookajorn T, Lee MCS. Kümpornsin K, et al. Among authors: pearson rd. Nat Commun. 2023 May 27;14(1):3059. doi: 10.1038/s41467-023-38774-1. Nat Commun. 2023. PMID: 37244916 Free PMC article.
Bayesian refinement of association signals for 14 loci in 3 common diseases.
Wellcome Trust Case Control Consortium; Maller JB, McVean G, Byrnes J, Vukcevic D, Palin K, Su Z, Howson JM, Auton A, Myers S, Morris A, Pirinen M, Brown MA, Burton PR, Caulfield MJ, Compston A, Farrall M, Hall AS, Hattersley AT, Hill AV, Mathew CG, Pembrey M, Satsangi J, Stratton MR, Worthington J, Craddock N, Hurles M, Ouwehand W, Parkes M, Rahman N, Duncanson A, Todd JA, Kwiatkowski DP, Samani NJ, Gough SC, McCarthy MI, Deloukas P, Donnelly P. Wellcome Trust Case Control Consortium, et al. Nat Genet. 2012 Dec;44(12):1294-301. doi: 10.1038/ng.2435. Epub 2012 Oct 28. Nat Genet. 2012. PMID: 23104008 Free PMC article.
265 results