Mapara MY - Search Results

1

Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation.

Liu A, Li S, Donnenberg V, Fu J, Gollin SM, Ma H, Lu C, Stolz DB, Mapara MY, Monaghan SA, Lentzsch S. Liu A, et al. Among authors: mapara my. Haematologica. 2018 Oct;103(10):1688-1697. doi: 10.3324/haematol.2018.188227. Epub 2018 Jun 28. Haematologica. 2018. PMID: 29954930 Free PMC article.

2

IMiD immunomodulatory compounds block C/EBP{beta} translation through eIF4E down-regulation resulting in inhibition of MM.

Li S, Pal R, Monaghan SA, Schafer P, Ouyang H, Mapara M, Galson DL, Lentzsch S. Li S, et al. Blood. 2011 May 12;117(19):5157-65. doi: 10.1182/blood-2010-10-314278. Epub 2011 Mar 9. Blood. 2011. PMID: 21389327 Free PMC article.

3

IMiD compounds affect CD34⁺ cell fate and maturation via CRBN-induced IKZF1 degradation.

Li S, Fu J, Wang H, Ma H, Xu X, Yang YG, Deng S, Mapara MY, Lentzsch S. Li S, et al. Among authors: mapara my. Blood Adv. 2018 Mar 13;2(5):492-504. doi: 10.1182/bloodadvances.2017010348. Blood Adv. 2018. PMID: 29496670 Free PMC article.

4

Thalidomide derivative CC-4047 inhibits osteoclast formation by down-regulation of PU.1.

Anderson G, Gries M, Kurihara N, Honjo T, Anderson J, Donnenberg V, Donnenberg A, Ghobrial I, Mapara MY, Stirling D, Roodman D, Lentzsch S. Anderson G, et al. Among authors: mapara my. Blood. 2006 Apr 15;107(8):3098-105. doi: 10.1182/blood-2005-08-3450. Epub 2005 Dec 22. Blood. 2006. PMID: 16373662 Free article.

5

Immunomodulatory derivatives induce PU.1 down-regulation, myeloid maturation arrest, and neutropenia.

Pal R, Monaghan SA, Hassett AC, Mapara MY, Schafer P, Roodman GD, Ragni MV, Moscinski L, List A, Lentzsch S. Pal R, et al. Among authors: mapara my. Blood. 2010 Jan 21;115(3):605-14. doi: 10.1182/blood-2009-05-221077. Epub 2009 Nov 25. Blood. 2010. PMID: 19965623 Free article.

6

Elevated Translation Initiation Factor eIF4E Is an Attractive Therapeutic Target in Multiple Myeloma.

Li S, Fu J, Lu C, Mapara MY, Raza S, Hengst U, Lentzsch S. Li S, et al. Among authors: mapara my. Mol Cancer Ther. 2016 Apr;15(4):711-9. doi: 10.1158/1535-7163.MCT-15-0798. Epub 2016 Mar 3. Mol Cancer Ther. 2016. PMID: 26939700

7

Targeting the GCK pathway: a novel and selective therapeutic strategy against RAS-mutated multiple myeloma.

Li S, Fu J, Yang J, Ma H, Bhutani D, Mapara MY, Marcireau C, Lentzsch S. Li S, et al. Among authors: mapara my. Blood. 2021 Apr 1;137(13):1754-1764. doi: 10.1182/blood.2020006334. Blood. 2021. PMID: 33036022 Free PMC article.

8

Absence of Stat1 in donor CD4⁺ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice.

Ma H, Lu C, Ziegler J, Liu A, Sepulveda A, Okada H, Lentzsch S, Mapara MY. Ma H, et al. Among authors: mapara my. J Clin Invest. 2011 Jul;121(7):2554-69. doi: 10.1172/JCI43706. Epub 2011 Jun 13. J Clin Invest. 2011. PMID: 21670504 Free PMC article.

9

Targeting the microtubular network as a new antimyeloma strategy.

Feng R, Li S, Lu C, Andreas C, Stolz DB, Mapara MY, Lentzsch S. Feng R, et al. Among authors: mapara my. Mol Cancer Ther. 2011 Oct;10(10):1886-96. doi: 10.1158/1535-7163.MCT-11-0234. Epub 2011 Aug 8. Mol Cancer Ther. 2011. PMID: 21825007

10

Longitudinal bone marrow evaluations for myelodysplasia in patients with myeloma before and after treatment with lenalidomide.

Monaghan SA, Dai L, Mapara MY, Normolle DP, Gollin SM, Lentzsch S. Monaghan SA, et al. Among authors: mapara my. Leuk Lymphoma. 2013 Sep;54(9):1965-74. doi: 10.3109/10428194.2012.755177. Epub 2013 Jan 28. Leuk Lymphoma. 2013. PMID: 23216269 Free PMC article.

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