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Clarin-1 gene transfer rescues auditory synaptopathy in model of Usher syndrome.
Dulon D, Papal S, Patni P, Cortese M, Vincent PF, Tertrais M, Emptoz A, Tlili A, Bouleau Y, Michel V, Delmaghani S, Aghaie A, Pepermans E, Alegria-Prevot O, Akil O, Lustig L, Avan P, Safieddine S, Petit C, El-Amraoui A. Dulon D, et al. Among authors: akil o. J Clin Invest. 2018 Aug 1;128(8):3382-3401. doi: 10.1172/JCI94351. Epub 2018 Jul 9. J Clin Invest. 2018. PMID: 29985171 Free PMC article.
Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G.
Emptoz A, Michel V, Lelli A, Akil O, Boutet de Monvel J, Lahlou G, Meyer A, Dupont T, Nouaille S, Ey E, Franca de Barros F, Beraneck M, Dulon D, Hardelin JP, Lustig L, Avan P, Petit C, Safieddine S. Emptoz A, et al. Among authors: akil o. Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):9695-9700. doi: 10.1073/pnas.1708894114. Epub 2017 Aug 23. Proc Natl Acad Sci U S A. 2017. PMID: 28835534 Free PMC article.
Cochlear gene therapy.
Lustig LR, Akil O. Lustig LR, et al. Among authors: akil o. Curr Opin Neurol. 2012 Feb;25(1):57-60. doi: 10.1097/WCO.0b013e32834f038c. Curr Opin Neurol. 2012. PMID: 22157110 Free PMC article. Review.
Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model.
Akil O, Dyka F, Calvet C, Emptoz A, Lahlou G, Nouaille S, Boutet de Monvel J, Hardelin JP, Hauswirth WW, Avan P, Petit C, Safieddine S, Lustig LR. Akil O, et al. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4496-4501. doi: 10.1073/pnas.1817537116. Epub 2019 Feb 19. Proc Natl Acad Sci U S A. 2019. PMID: 30782832 Free PMC article.
Cochlear Gene Therapy.
Lustig L, Akil O. Lustig L, et al. Among authors: akil o. Cold Spring Harb Perspect Med. 2019 Sep 3;9(9):a033191. doi: 10.1101/cshperspect.a033191. Cold Spring Harb Perspect Med. 2019. PMID: 30323014 Free PMC article. Review.
AAV-Mediated Gene Delivery to the Inner Ear.
Akil O, Lustig L. Akil O, et al. Methods Mol Biol. 2019;1950:271-282. doi: 10.1007/978-1-4939-9139-6_16. Methods Mol Biol. 2019. PMID: 30783980
35 results