Kirihara T - Search Results

1

Identification of a Selective, Non-Prostanoid EP2 Receptor Agonist for the Treatment of Glaucoma: Omidenepag and its Prodrug Omidenepag Isopropyl.

Iwamura R, Tanaka M, Okanari E, Kirihara T, Odani-Kawabata N, Shams N, Yoneda K. Iwamura R, et al. Among authors: kirihara t. J Med Chem. 2018 Aug 9;61(15):6869-6891. doi: 10.1021/acs.jmedchem.8b00808. Epub 2018 Jul 30. J Med Chem. 2018. PMID: 29995405

2

Pharmacologic Characterization of Omidenepag Isopropyl, a Novel Selective EP2 Receptor Agonist, as an Ocular Hypotensive Agent.

Kirihara T, Taniguchi T, Yamamura K, Iwamura R, Yoneda K, Odani-Kawabata N, Shimazaki A, Matsugi T, Shams N, Zhang JZ. Kirihara T, et al. Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):145-153. doi: 10.1167/iovs.17-22745. Invest Ophthalmol Vis Sci. 2018. PMID: 29332128

3

Additive Intraocular Pressure-Lowering Effects of a Novel Selective EP2 Receptor Agonist, Omidenepag Isopropyl, Combined with Existing Antiglaucoma Agents in Conscious Ocular Normotensive Monkeys.

Fuwa M, Shimazaki A, Odani-Kawabata N, Kirihara T, Taniguchi T, Iwamura R, Yoneda K, Kato M, Morishima K, Shams NK. Fuwa M, et al. Among authors: kirihara t. J Ocul Pharmacol Ther. 2021 May;37(4):223-229. doi: 10.1089/jop.2020.0071. Epub 2021 Feb 17. J Ocul Pharmacol Ther. 2021. PMID: 33600237

4

Advantages of Efficacy and Safety of Fixed-Dose Tafluprost/Timolol Combination Over Fixed-Dose Latanoprost/Timolol Combination.

Fuwa M, Ueda K, Akaishi T, Yamashita N, Kirihara T, Shimazaki A, Mano H, Kawazu K. Fuwa M, et al. Among authors: kirihara t. PLoS One. 2016 Jul 6;11(7):e0158797. doi: 10.1371/journal.pone.0158797. eCollection 2016. PLoS One. 2016. PMID: 27383260 Free PMC article.

5

Effects of the new ethacrynic acid derivative SA9000 on intraocular pressure in cats and monkeys.

Shimazaki A, Ichikawa M, Rao PV, Kirihara T, Konomi K, Epstein DL, Hara H. Shimazaki A, et al. Among authors: kirihara t. Biol Pharm Bull. 2004 Jul;27(7):1019-24. doi: 10.1248/bpb.27.1019. Biol Pharm Bull. 2004. PMID: 15256733 Free article.

6

Effects of the new ethacrynic acid oxime derivative SA12590 on intraocular pressure in cats and monkeys.

Shimazaki A, Kirihara T, Rao PV, Tajima H, Matsugi T, Epstein DL. Shimazaki A, et al. Among authors: kirihara t. Biol Pharm Bull. 2007 Aug;30(8):1445-9. doi: 10.1248/bpb.30.1445. Biol Pharm Bull. 2007. PMID: 17666801 Free article.

7

Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity.

Tsutsumi T, Iwao K, Hayashi H, Kirihara T, Kawaji T, Inoue T, Hino S, Nakao M, Tanihara H. Tsutsumi T, et al. Among authors: kirihara t. Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):6461-6473. doi: 10.1167/iovs.16-19494. Invest Ophthalmol Vis Sci. 2016. PMID: 27893888

8

Ocular hypotensive efficacy of Src-family tyrosine kinase inhibitors via different cellular actions from Rock inhibitors.

Kirihara T, Shimazaki A, Nakamura M, Miyawaki N. Kirihara T, et al. Exp Eye Res. 2014 Feb;119:97-105. doi: 10.1016/j.exer.2013.11.015. Epub 2013 Dec 7. Exp Eye Res. 2014. PMID: 24321889

9

Molecular biomarkers in glaucoma.

Bhattacharya SK, Lee RK, Grus FH; Seventh ARVO/Pfizer Ophthalmics Research Institute Conference Working Group. Bhattacharya SK, et al. Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):121-31. doi: 10.1167/iovs.12-11067. Invest Ophthalmol Vis Sci. 2013. PMID: 23297392 Free PMC article. No abstract available.

10

Prolonged recovery of ultraviolet B-irradiated skin in neuropsin (KLK8)-deficient mice.

Kirihara T, Matsumoto-Miyai K, Nakamura Y, Sadayama T, Yoshida S, Shiosaka S. Kirihara T, et al. Br J Dermatol. 2003 Oct;149(4):700-6. doi: 10.1046/j.1365-2133.2003.05484.x. Br J Dermatol. 2003. PMID: 14616360

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