Grimm FA - Search Results

1

A human population-based organotypic in vitro model for cardiotoxicity screening.

Grimm FA, Blanchette A, House JS, Ferguson K, Hsieh NH, Dalaijamts C, Wright AA, Anson B, Wright FA, Chiu WA, Rusyn I. Grimm FA, et al. ALTEX. 2018;35(4):441-452. doi: 10.14573/altex.1805301. Epub 2018 Jul 8. ALTEX. 2018. PMID: 29999168 Free PMC article.

2

High-Content Assay Multiplexing for Toxicity Screening in Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Hepatocytes.

Grimm FA, Iwata Y, Sirenko O, Bittner M, Rusyn I. Grimm FA, et al. Assay Drug Dev Technol. 2015 Nov;13(9):529-46. doi: 10.1089/adt.2015.659. Epub 2015 Nov 5. Assay Drug Dev Technol. 2015. PMID: 26539751 Free PMC article.

3

A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives.

Grimm FA, Iwata Y, Sirenko O, Chappell GA, Wright FA, Reif DM, Braisted J, Gerhold DL, Yeakley JM, Shepard P, Seligmann B, Roy T, Boogaard PJ, Ketelslegers HB, Rohde AM, Rusyn I. Grimm FA, et al. Green Chem. 2016 Aug 21;18(16):4407-4419. doi: 10.1039/c6gc01147k. Epub 2016 May 16. Green Chem. 2016. PMID: 28035192 Free PMC article.

4

In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model.

Sirenko O, Grimm FA, Ryan KR, Iwata Y, Chiu WA, Parham F, Wignall JA, Anson B, Cromwell EF, Behl M, Rusyn I, Tice RR. Sirenko O, et al. Among authors: grimm fa. Toxicol Appl Pharmacol. 2017 May 1;322:60-74. doi: 10.1016/j.taap.2017.02.020. Epub 2017 Mar 1. Toxicol Appl Pharmacol. 2017. PMID: 28259702 Free PMC article.

5

Grouping of Petroleum Substances as Example UVCBs by Ion Mobility-Mass Spectrometry to Enable Chemical Composition-Based Read-Across.

Grimm FA, Russell WK, Luo YS, Iwata Y, Chiu WA, Roy T, Boogaard PJ, Ketelslegers HB, Rusyn I. Grimm FA, et al. Environ Sci Technol. 2017 Jun 20;51(12):7197-7207. doi: 10.1021/acs.est.6b06413. Epub 2017 May 26. Environ Sci Technol. 2017. PMID: 28502166 Free PMC article.

6

High-Content Assay Multiplexing for Vascular Toxicity Screening in Induced Pluripotent Stem Cell-Derived Endothelial Cells and Human Umbilical Vein Endothelial Cells.

Iwata Y, Klaren WD, Lebakken CS, Grimm FA, Rusyn I. Iwata Y, et al. Among authors: grimm fa. Assay Drug Dev Technol. 2017 Aug/Sep;15(6):267-279. doi: 10.1089/adt.2017.786. Epub 2017 Aug 3. Assay Drug Dev Technol. 2017. PMID: 28771372 Free PMC article.

7

A Pipeline for High-Throughput Concentration Response Modeling of Gene Expression for Toxicogenomics.

House JS, Grimm FA, Jima DD, Zhou YH, Rusyn I, Wright FA. House JS, et al. Among authors: grimm fa. Front Genet. 2017 Nov 1;8:168. doi: 10.3389/fgene.2017.00168. eCollection 2017. Front Genet. 2017. PMID: 29163636 Free PMC article.

8

ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models.

Marvel SW, To K, Grimm FA, Wright FA, Rusyn I, Reif DM. Marvel SW, et al. Among authors: grimm fa. BMC Bioinformatics. 2018 Mar 5;19(1):80. doi: 10.1186/s12859-018-2089-2. BMC Bioinformatics. 2018. PMID: 29506467 Free PMC article.

9

Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip.

Sakolish C, Weber EJ, Kelly EJ, Himmelfarb J, Mouneimne R, Grimm FA, House JS, Wade T, Han A, Chiu WA, Rusyn I. Sakolish C, et al. Among authors: grimm fa. Sci Rep. 2018 Oct 5;8(1):14882. doi: 10.1038/s41598-018-33099-2. Sci Rep. 2018. PMID: 30291268 Free PMC article.

10

Thorough QT/QTc in a Dish: An In Vitro Human Model That Accurately Predicts Clinical Concentration-QTc Relationships.

Blanchette AD, Grimm FA, Dalaijamts C, Hsieh NH, Ferguson K, Luo YS, Rusyn I, Chiu WA. Blanchette AD, et al. Among authors: grimm fa. Clin Pharmacol Ther. 2019 May;105(5):1175-1186. doi: 10.1002/cpt.1259. Epub 2018 Dec 2. Clin Pharmacol Ther. 2019. PMID: 30346629 Free PMC article.

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