Leitges M - Search Results

1

PKCα integrates spatiotemporally distinct Ca²⁺ and autocrine BDNF signaling to facilitate synaptic plasticity.

Colgan LA, Hu M, Misler JA, Parra-Bueno P, Moran CM, Leitges M, Yasuda R. Colgan LA, et al. Among authors: leitges m. Nat Neurosci. 2018 Aug;21(8):1027-1037. doi: 10.1038/s41593-018-0184-3. Epub 2018 Jul 16. Nat Neurosci. 2018. PMID: 30013171 Free PMC article.

2

Knockout of PKC alpha enhances insulin signaling through PI3K.

Leitges M, Plomann M, Standaert ML, Bandyopadhyay G, Sajan MP, Kanoh Y, Farese RV. Leitges M, et al. Mol Endocrinol. 2002 Apr;16(4):847-58. doi: 10.1210/mend.16.4.0809. Mol Endocrinol. 2002. PMID: 11923480

3

A role for the beta isoform of protein kinase C in fear conditioning.

Weeber EJ, Atkins CM, Selcher JC, Varga AW, Mirnikjoo B, Paylor R, Leitges M, Sweatt JD. Weeber EJ, et al. Among authors: leitges m. J Neurosci. 2000 Aug 15;20(16):5906-14. doi: 10.1523/JNEUROSCI.20-16-05906.2000. J Neurosci. 2000. PMID: 10934237 Free PMC article.

4

Protein kinase C is a calcium sensor for presynaptic short-term plasticity.

Fioravante D, Chu Y, de Jong AP, Leitges M, Kaeser PS, Regehr WG. Fioravante D, et al. Among authors: leitges m. Elife. 2014 Aug 5;3:e03011. doi: 10.7554/eLife.03011. Elife. 2014. Retraction in: Elife. 2018 Mar 07;7:e35974. doi: 10.7554/eLife.35974 PMID: 25097249 Free PMC article. Retracted.

5

Calcium-dependent PKC isoforms have specialized roles in short-term synaptic plasticity.

Chu Y, Fioravante D, Leitges M, Regehr WG. Chu Y, et al. Among authors: leitges m. Neuron. 2014 May 21;82(4):859-71. doi: 10.1016/j.neuron.2014.04.003. Epub 2014 May 1. Neuron. 2014. PMID: 24794094 Free PMC article.

6

Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia.

Liou GY, Döppler H, Braun UB, Panayiotou R, Scotti Buzhardt M, Radisky DC, Crawford HC, Fields AP, Murray NR, Wang QJ, Leitges M, Storz P. Liou GY, et al. Among authors: leitges m. Nat Commun. 2015 Feb 20;6:6200. doi: 10.1038/ncomms7200. Nat Commun. 2015. PMID: 25698580 Free PMC article.

7

A redundant role for PKC-epsilon in mast cell signaling and effector function.

Lessmann E, Leitges M, Huber M. Lessmann E, et al. Among authors: leitges m. Int Immunol. 2006 May;18(5):767-73. doi: 10.1093/intimm/dxl012. Epub 2006 Mar 28. Int Immunol. 2006. PMID: 16569674

8

Functional PKC in vivo analysis using deficient mouse models.

Leitges M. Leitges M. Biochem Soc Trans. 2007 Nov;35(Pt 5):1018-20. doi: 10.1042/BST0351018. Biochem Soc Trans. 2007. PMID: 17956267 Review.

9

Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer's disease.

Alfonso SI, Callender JA, Hooli B, Antal CE, Mullin K, Sherman MA, Lesné SE, Leitges M, Newton AC, Tanzi RE, Malinow R. Alfonso SI, et al. Among authors: leitges m. Sci Signal. 2016 May 10;9(427):ra47. doi: 10.1126/scisignal.aaf6209. Sci Signal. 2016. PMID: 27165780 Free PMC article.

10

Protein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis.

Hill KS, Erdogan E, Khoor A, Walsh MP, Leitges M, Murray NR, Fields AP. Hill KS, et al. Among authors: leitges m. Oncogene. 2014 Apr 17;33(16):2134-44. doi: 10.1038/onc.2013.147. Epub 2013 Apr 22. Oncogene. 2014. PMID: 23604119 Free PMC article.

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