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Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893.
Tabor DE, Yu L, Mok H, Tkaczyk C, Sellman BR, Wu Y, Oganesyan V, Slidel T, Jafri H, McCarthy M, Bradford P, Esser MT. Tabor DE, et al. Among authors: oganesyan v. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5312-21. doi: 10.1128/AAC.00357-16. Print 2016 Sep. Antimicrob Agents Chemother. 2016. PMID: 27324766 Free PMC article.
Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity In Vitro and Staphylococcus aureus Fitness in Infection Models.
Tkaczyk C, Semenova E, Shi YY, Rosenthal K, Oganesyan V, Warrener P, Stover CK, Sellman BR. Tkaczyk C, et al. Among authors: oganesyan v. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01033-18. doi: 10.1128/AAC.01033-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30150481 Free PMC article.
Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody.
Oganesyan V, Peng L, Bee JS, Li J, Perry SR, Comer F, Xu L, Cook K, Senthil K, Clarke L, Rosenthal K, Gao C, Damschroder M, Wu H, Dall'Acqua W. Oganesyan V, et al. J Biol Chem. 2018 Jun 1;293(22):8439-8448. doi: 10.1074/jbc.M117.818013. Epub 2018 Apr 18. J Biol Chem. 2018. PMID: 29669810 Free PMC article.
Long-acting antibody ligand mimetics for HER4-selective agonism.
Shan L, Cook KM, Haskins N, Omar B, Jiang Y, Garcia A, Koksal A, Oganesyan V, Rosenthal K, Wu H, Dall'Acqua WF, Damschroder MM. Shan L, et al. Among authors: oganesyan v. Sci Rep. 2020 Oct 14;10(1):17257. doi: 10.1038/s41598-020-74176-9. Sci Rep. 2020. PMID: 33057063 Free PMC article.
Generation and Characterization of an IgG4 Monomeric Fc Platform.
Shan L, Colazet M, Rosenthal KL, Yu XQ, Bee JS, Ferguson A, Damschroder MM, Wu H, Dall'Acqua WF, Tsui P, Oganesyan V. Shan L, et al. Among authors: oganesyan v. PLoS One. 2016 Aug 1;11(8):e0160345. doi: 10.1371/journal.pone.0160345. eCollection 2016. PLoS One. 2016. PMID: 27479095 Free PMC article.
Mechanisms of neutralization of a human anti-α-toxin antibody.
Oganesyan V, Peng L, Damschroder MM, Cheng L, Sadowska A, Tkaczyk C, Sellman BR, Wu H, Dall'Acqua WF. Oganesyan V, et al. J Biol Chem. 2014 Oct 24;289(43):29874-80. doi: 10.1074/jbc.M114.601328. Epub 2014 Sep 10. J Biol Chem. 2014. PMID: 25210036 Free PMC article.
94 results