Hu W - Search Results

1

Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes.

Guan D, Xiong Y, Borck PC, Jang C, Doulias PT, Papazyan R, Fang B, Jiang C, Zhang Y, Briggs ER, Hu W, Steger D, Ischiropoulos H, Rabinowitz JD, Lazar MA. Guan D, et al. Among authors: hu w. Cell. 2018 Aug 9;174(4):831-842.e12. doi: 10.1016/j.cell.2018.06.031. Epub 2018 Jul 26. Cell. 2018. PMID: 30057115 Free PMC article.

2

Patient Adipose Stem Cell-Derived Adipocytes Reveal Genetic Variation that Predicts Antidiabetic Drug Response.

Hu W, Jiang C, Guan D, Dierickx P, Zhang R, Moscati A, Nadkarni GN, Steger DJ, Loos RJF, Hu C, Jia W, Soccio RE, Lazar MA. Hu W, et al. Among authors: hu c. Cell Stem Cell. 2019 Feb 7;24(2):299-308.e6. doi: 10.1016/j.stem.2018.11.018. Epub 2019 Jan 10. Cell Stem Cell. 2019. PMID: 30639037 Free PMC article.

3

Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-associated gene.

Benson KK, Hu W, Weller AH, Bennett AH, Chen ER, Khetarpal SA, Yoshino S, Bone WP, Wang L, Rabinowitz JD, Voight BF, Soccio RE. Benson KK, et al. Among authors: hu w. Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):23232-23242. doi: 10.1073/pnas.1913199116. Epub 2019 Oct 28. Proc Natl Acad Sci U S A. 2019. PMID: 31659023 Free PMC article.

4

The hepatocyte clock and feeding control chronophysiology of multiple liver cell types.

Guan D, Xiong Y, Trinh TM, Xiao Y, Hu W, Jiang C, Dierickx P, Jang C, Rabinowitz JD, Lazar MA. Guan D, et al. Among authors: hu w. Science. 2020 Sep 11;369(6509):1388-1394. doi: 10.1126/science.aba8984. Epub 2020 Jul 30. Science. 2020. PMID: 32732282 Free PMC article.

5

Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids.

Hu W, Jiang C, Kim M, Yang W, Zhu K, Guan D, Lv W, Xiao Y, Wilson JR, Rader DJ, Pui CH, Relling MV, Lazar MA. Hu W, et al. Cell Metab. 2021 Aug 3;33(8):1592-1609.e7. doi: 10.1016/j.cmet.2021.06.004. Epub 2021 Jul 6. Cell Metab. 2021. PMID: 34233159 Free PMC article.

6

Isoform-specific functions of PPARγ in gene regulation and metabolism.

Hu W, Jiang C, Kim M, Xiao Y, Richter HJ, Guan D, Zhu K, Krusen BM, Roberts AN, Miller J, Steger DJ, Lazar MA. Hu W, et al. Genes Dev. 2022 Mar 1;36(5-6):300-312. doi: 10.1101/gad.349232.121. Epub 2022 Mar 10. Genes Dev. 2022. PMID: 35273075 Free PMC article.

7

Modelling metabolic diseases and drug response using stem cells and organoids.

Hu W, Lazar MA. Hu W, et al. Nat Rev Endocrinol. 2022 Dec;18(12):744-759. doi: 10.1038/s41574-022-00733-z. Epub 2022 Sep 7. Nat Rev Endocrinol. 2022. PMID: 36071283 Free PMC article. Review.

8

Hepatocytes demarcated by EphB2 contribute to the progression of nonalcoholic steatohepatitis.

Xiao Y, Batmanov K, Hu W, Zhu K, Tom AY, Guan D, Jiang C, Cheng L, McCright SJ, Yang EC, Lanza MR, Liu Y, Hill DA, Lazar MA. Xiao Y, et al. Among authors: hu w. Sci Transl Med. 2023 Feb 8;15(682):eadc9653. doi: 10.1126/scitranslmed.adc9653. Epub 2023 Feb 8. Sci Transl Med. 2023. PMID: 36753562 Free PMC article.

9

Hepatocyte SREBP signaling mediates clock communication within the liver.

Guan D, Bae H, Zhou D, Chen Y, Jiang C, La CM, Xiao Y, Zhu K, Hu W, Trinh TM, Liu P, Xiong Y, Cai B, Jang C, Lazar MA. Guan D, et al. Among authors: hu w. J Clin Invest. 2023 Apr 17;133(8):e163018. doi: 10.1172/JCI163018. J Clin Invest. 2023. PMID: 37066875 Free PMC article.

10

An intrinsically disordered region controlling condensation of a circadian clock component and rhythmic transcription in the liver.

Zhu K, Celwyn IJ, Guan D, Xiao Y, Wang X, Hu W, Jiang C, Cheng L, Casellas R, Lazar MA. Zhu K, et al. Among authors: hu w. Mol Cell. 2023 Oct 5;83(19):3457-3469.e7. doi: 10.1016/j.molcel.2023.09.010. Mol Cell. 2023. PMID: 37802023 Free PMC article.

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