Griffith EC - Search Results

1

The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations in Staphylococcus aureus Dihydropteroate Synthase.

Griffith EC, Wallace MJ, Wu Y, Kumar G, Gajewski S, Jackson P, Phelps GA, Zheng Z, Rock CO, Lee RE, White SW. Griffith EC, et al. Front Microbiol. 2018 Jul 17;9:1369. doi: 10.3389/fmicb.2018.01369. eCollection 2018. Front Microbiol. 2018. PMID: 30065703 Free PMC article.

2

Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents.

Zhao Y, Shadrick WR, Wallace MJ, Wu Y, Griffith EC, Qi J, Yun MK, White SW, Lee RE. Zhao Y, et al. Among authors: griffith ec. Bioorg Med Chem Lett. 2016 Aug 15;26(16):3950-4. doi: 10.1016/j.bmcl.2016.07.006. Epub 2016 Jul 4. Bioorg Med Chem Lett. 2016. PMID: 27423480 Free PMC article.

3

Discovery and Characterization of the Antimetabolite Action of Thioacetamide-Linked 1,2,3-Triazoles as Disruptors of Cysteine Biosynthesis in Gram-Negative Bacteria.

Wallace MJ, Dharuman S, Fernando DM, Reeve SM, Gee CT, Yao J, Griffith EC, Phelps GA, Wright WC, Elmore JM, Lee RB, Chen T, Lee RE. Wallace MJ, et al. Among authors: griffith ec. ACS Infect Dis. 2020 Mar 13;6(3):467-478. doi: 10.1021/acsinfecdis.9b00406. Epub 2020 Jan 13. ACS Infect Dis. 2020. PMID: 31887254 Free PMC article.

4

Development of a pterin-based fluorescent probe for screening dihydropteroate synthase.

Zhao Y, Hammoudeh D, Lin W, Das S, Yun MK, Li Z, Griffith E, Chen T, White SW, Lee RE. Zhao Y, et al. Bioconjug Chem. 2011 Oct 19;22(10):2110-7. doi: 10.1021/bc200346e. Epub 2011 Sep 30. Bioconjug Chem. 2011. PMID: 21916405 Free PMC article.

5

Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase.

Hammoudeh DI, Daté M, Yun MK, Zhang W, Boyd VA, Viacava Follis A, Griffith E, Lee RE, Bashford D, White SW. Hammoudeh DI, et al. ACS Chem Biol. 2014 Jun 20;9(6):1294-302. doi: 10.1021/cb500038g. Epub 2014 Mar 27. ACS Chem Biol. 2014. PMID: 24650357 Free PMC article.

6

Ureadepsipeptides as ClpP Activators.

Griffith EC, Zhao Y, Singh AP, Conlon BP, Tangallapally R, Shadrick WR, Liu J, Wallace MJ, Yang L, Elmore JM, Li Y, Zheng Z, Miller DJ, Cheramie MN, Lee RB, LaFleur MD, Lewis K, Lee RE. Griffith EC, et al. ACS Infect Dis. 2019 Nov 8;5(11):1915-1925. doi: 10.1021/acsinfecdis.9b00245. Epub 2019 Oct 24. ACS Infect Dis. 2019. PMID: 31588734 Free PMC article.

7

Biophysical analysis of the Mycobacteria tuberculosis peptide binding protein DppA reveals a stringent peptide binding pocket.

Fernando DM, Gee CT, Griffith EC, Meyer CJ, Wilt LA, Tangallapally R, Wallace MJ, Miller DJ, Lee RE. Fernando DM, et al. Among authors: griffith ec. Tuberculosis (Edinb). 2022 Jan;132:102157. doi: 10.1016/j.tube.2021.102157. Epub 2021 Nov 29. Tuberculosis (Edinb). 2022. PMID: 34894561 Free PMC article.

8

Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.

Yang SW, Huang X, Lin W, Min J, Miller DJ, Mayasundari A, Rodrigues P, Griffith EC, Gee CT, Li L, Li W, Lee RE, Rankovic Z, Chen T, Potts PR. Yang SW, et al. Among authors: griffith ec. Nat Commun. 2020 Oct 1;11(1):4931. doi: 10.1038/s41467-020-18708-x. Nat Commun. 2020. PMID: 33004795 Free PMC article.

9

In Vivo and In Vitro Effects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci.

Brown Gandt A, Griffith EC, Lister IM, Billings LL, Han A, Tangallapally R, Zhao Y, Singh AP, Lee RE, LaFleur MD. Brown Gandt A, et al. Among authors: griffith ec. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00424-18. doi: 10.1128/AAC.00424-18. Print 2018 Aug. Antimicrob Agents Chemother. 2018. PMID: 29784838 Free PMC article.

10

Mechanistic Insight on the Mode of Action of Colletoic Acid.

Ling T, Miller DJ, Lang WH, Griffith E, Rodriguez-Cortes A, El Ayachi I, Palacios G, Min J, Miranda-Carboni G, Lee RE, Rivas F. Ling T, et al. J Med Chem. 2019 Aug 8;62(15):6925-6940. doi: 10.1021/acs.jmedchem.9b00187. Epub 2019 Jul 24. J Med Chem. 2019. PMID: 31294974 Free PMC article.

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