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Subjugation of TGFβ Signaling by Human Papilloma Virus in Head and Neck Squamous Cell Carcinoma Shifts DNA Repair from Homologous Recombination to Alternative End Joining.
Liu Q, Ma L, Jones T, Palomero L, Pujana MA, Martinez-Ruiz H, Ha PK, Murnane J, Cuartas I, Seoane J, Baumann M, Linge A, Barcellos-Hoff MH. Liu Q, et al. Among authors: murnane j. Clin Cancer Res. 2018 Dec 1;24(23):6001-6014. doi: 10.1158/1078-0432.CCR-18-1346. Epub 2018 Aug 7. Clin Cancer Res. 2018. PMID: 30087144
Misrepair in Context: TGFβ Regulation of DNA Repair.
Liu Q, Lopez K, Murnane J, Humphrey T, Barcellos-Hoff MH. Liu Q, et al. Among authors: murnane j. Front Oncol. 2019 Aug 27;9:799. doi: 10.3389/fonc.2019.00799. eCollection 2019. Front Oncol. 2019. PMID: 31552165 Free PMC article. Review.
Loss of TGFβ signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types.
Liu Q, Palomero L, Moore J, Guix I, Espín R, Aytés A, Mao JH, Paulovich AG, Whiteaker JR, Ivey RG, Iliakis G, Luo D, Chalmers AJ, Murnane J, Pujana MA, Barcellos-Hoff MH. Liu Q, et al. Among authors: murnane j. Sci Transl Med. 2021 Feb 10;13(580):eabc4465. doi: 10.1126/scitranslmed.abc4465. Sci Transl Med. 2021. PMID: 33568520 Free PMC article.
113 results