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FOXM1 contributes to treatment failure in acute myeloid leukemia.
Khan I, Halasi M, Patel A, Schultz R, Kalakota N, Chen YH, Aardsma N, Liu L, Crispino JD, Mahmud N, Frankfurt O, Gartel AL. Khan I, et al. Among authors: crispino jd. JCI Insight. 2018 Aug 9;3(15):e121583. doi: 10.1172/jci.insight.121583. eCollection 2018 Aug 9. JCI Insight. 2018. PMID: 30089730 Free PMC article.
Myeloid leukemia in Down syndrome.
Khan I, Malinge S, Crispino J. Khan I, et al. Crit Rev Oncog. 2011;16(1-2):25-36. doi: 10.1615/critrevoncog.v16.i1-2.40. Crit Rev Oncog. 2011. PMID: 22150305 Free PMC article. Review.
AKT is a therapeutic target in myeloproliferative neoplasms.
Khan I, Huang Z, Wen Q, Stankiewicz MJ, Gilles L, Goldenson B, Schultz R, Diebold L, Gurbuxani S, Finke CM, Lasho TL, Koppikar P, Pardanani A, Stein B, Altman JK, Levine RL, Tefferi A, Crispino JD. Khan I, et al. Among authors: crispino jd. Leukemia. 2013 Sep;27(9):1882-90. doi: 10.1038/leu.2013.167. Epub 2013 Jun 10. Leukemia. 2013. PMID: 23748344 Free PMC article.
Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition.
Wen QJ, Yang Q, Goldenson B, Malinge S, Lasho T, Schneider RK, Breyfogle LJ, Schultz R, Gilles L, Koppikar P, Abdel-Wahab O, Pardanani A, Stein B, Gurbuxani S, Mullally A, Levine RL, Tefferi A, Crispino JD. Wen QJ, et al. Among authors: crispino jd. Nat Med. 2015 Dec;21(12):1473-80. doi: 10.1038/nm.3995. Epub 2015 Nov 16. Nat Med. 2015. PMID: 26569382 Free PMC article.
Aurora Kinase A Inhibition Provides Clinical Benefit, Normalizes Megakaryocytes, and Reduces Bone Marrow Fibrosis in Patients with Myelofibrosis: A Phase I Trial.
Gangat N, Marinaccio C, Swords R, Watts JM, Gurbuxani S, Rademaker A, Fought AJ, Frankfurt O, Altman JK, Wen QJ, Farnoud N, Famulare CA, Patel A, Tapia R, Vallapureddy RR, Barath S, Graf A, Handlogten A, Zblewski D, Patnaik MM, Al-Kali A, Dinh YT, Englund Prahl K, Patel S, Nobrega JC, Tejera D, Thomassen A, Gao J, Ji P, Rampal RK, Giles FJ, Tefferi A, Stein B, Crispino JD. Gangat N, et al. Among authors: crispino jd. Clin Cancer Res. 2019 Aug 15;25(16):4898-4906. doi: 10.1158/1078-0432.CCR-19-1005. Epub 2019 May 6. Clin Cancer Res. 2019. PMID: 31061068
Acute Megakaryocytic Leukemia.
McNulty M, Crispino JD. McNulty M, et al. Among authors: crispino jd. Cold Spring Harb Perspect Med. 2020 Feb 3;10(2):a034884. doi: 10.1101/cshperspect.a034884. Cold Spring Harb Perspect Med. 2020. PMID: 31548219 Free PMC article. Review.
172 results