El-Naggar AM - Search Results

1

Novel Tetrahydrobenzo [b] Thiophene Compounds Exhibit Anticancer Activity through Enhancing Apoptosis and Inhibiting Tyrosine Kinase.

El-Metwally SA, Khalil AK, El-Naggar AM, El-Sayed WM. El-Metwally SA, et al. Anticancer Agents Med Chem. 2018;18(12):1761-1769. doi: 10.2174/1871520618666180813120558. Anticancer Agents Med Chem. 2018. PMID: 30101717

2

Design, synthesis, molecular modeling and biological evaluation of novel 1H-pyrazolo[3,4-b]pyridine derivatives as potential anticancer agents.

Eissa IH, El-Naggar AM, El-Hashash MA. Eissa IH, et al. Bioorg Chem. 2016 Aug;67:43-56. doi: 10.1016/j.bioorg.2016.05.006. Epub 2016 May 20. Bioorg Chem. 2016. PMID: 27253830

3

Eco-friendly Synthesis of Pyrido[2,3-d]pyrimidine Analogs and Their Anticancer and Tyrosine Kinase Inhibition Activities.

El-Naggar AM, Khalil AK, Zeidan HM, El-Sayed WM. El-Naggar AM, et al. Anticancer Agents Med Chem. 2017;17(12):1644-1651. doi: 10.2174/1871521409666170412130040. Anticancer Agents Med Chem. 2017. PMID: 28403776

4

Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities.

Abouzid KAM, Al-Ansary GH, El-Naggar AM. Abouzid KAM, et al. Eur J Med Chem. 2017 Jul 7;134:357-365. doi: 10.1016/j.ejmech.2017.04.024. Epub 2017 Apr 14. Eur J Med Chem. 2017. PMID: 28431341

5

Design and Discovery of Novel Quinoxaline Derivatives as Dual DNA Intercalators and Topoisomerase II Inhibitors.

Eissa IH, El-Naggar AM, El-Sattar NEAA, Youssef ASA. Eissa IH, et al. Anticancer Agents Med Chem. 2018;18(2):195-209. doi: 10.2174/1871520617666170710182405. Anticancer Agents Med Chem. 2018. PMID: 28699490

6

Synthesis, characterization and molecular docking studies of thiouracil derivatives as potent thymidylate synthase inhibitors and potential anticancer agents.

El-Naggar AM, Abou-El-Regal MM, El-Metwally SA, Sherbiny FF, Eissa IH. El-Naggar AM, et al. Mol Divers. 2017 Nov;21(4):967-983. doi: 10.1007/s11030-017-9776-1. Epub 2017 Aug 16. Mol Divers. 2017. PMID: 28815411

7

Novel Nicotinonitrile Derivatives Bearing Imino Moieties Enhance Apoptosis and Inhibit Tyrosine Kinase.

El-Hashash MA, El-Bordany EA, Marzouk MI, El-Naggar AM, Nawar TMS, El-Sayed WM. El-Hashash MA, et al. Anticancer Agents Med Chem. 2018;18(11):1589-1598. doi: 10.2174/1871520618666180510112614. Anticancer Agents Med Chem. 2018. PMID: 29745342

8

Design, synthesis, anticancer evaluation and docking studies of new pyrimidine derivatives as potent thymidylate synthase inhibitors.

Amin LHT, Shawer TZ, El-Naggar AM, El-Sehrawi HMA. Amin LHT, et al. Bioorg Chem. 2019 Oct;91:103159. doi: 10.1016/j.bioorg.2019.103159. Epub 2019 Jul 29. Bioorg Chem. 2019. PMID: 31382056

9

Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers.

Abbass EM, Khalil AK, Mohamed MM, Eissa IH, El-Naggar AM. Abbass EM, et al. Bioorg Chem. 2020 Nov;104:104255. doi: 10.1016/j.bioorg.2020.104255. Epub 2020 Sep 2. Bioorg Chem. 2020. PMID: 32927130

10

Eco-friendly sequential one-pot synthesis, molecular docking, and anticancer evaluation of arylidene-hydrazinyl-thiazole derivatives as CDK2 inhibitors.

El-Naggar AM, El-Hashash MA, Elkaeed EB. El-Naggar AM, et al. Bioorg Chem. 2021 Mar;108:104615. doi: 10.1016/j.bioorg.2020.104615. Epub 2021 Jan 5. Bioorg Chem. 2021. PMID: 33484942

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