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Page 1
Cryo-EM structures of the human volume-regulated anion channel LRRC8.
Kasuya G, Nakane T, Yokoyama T, Jia Y, Inoue M, Watanabe K, Nakamura R, Nishizawa T, Kusakizako T, Tsutsumi A, Yanagisawa H, Dohmae N, Hattori M, Ichijo H, Yan Z, Kikkawa M, Shirouzu M, Ishitani R, Nureki O. Kasuya G, et al. Among authors: tsutsumi a. Nat Struct Mol Biol. 2018 Sep;25(9):797-804. doi: 10.1038/s41594-018-0109-6. Epub 2018 Aug 20. Nat Struct Mol Biol. 2018. PMID: 30127360
Structure of the mitochondrial import gate reveals distinct preprotein paths.
Araiso Y, Tsutsumi A, Qiu J, Imai K, Shiota T, Song J, Lindau C, Wenz LS, Sakaue H, Yunoki K, Kawano S, Suzuki J, Wischnewski M, Schütze C, Ariyama H, Ando T, Becker T, Lithgow T, Wiedemann N, Pfanner N, Kikkawa M, Endo T. Araiso Y, et al. Among authors: tsutsumi a. Nature. 2019 Nov;575(7782):395-401. doi: 10.1038/s41586-019-1680-7. Epub 2019 Oct 10. Nature. 2019. PMID: 31600774
Structural analysis reveals TLR7 dynamics underlying antagonism.
Tojo S, Zhang Z, Matsui H, Tahara M, Ikeguchi M, Kochi M, Kamada M, Shigematsu H, Tsutsumi A, Adachi N, Shibata T, Yamamoto M, Kikkawa M, Senda T, Isobe Y, Ohto U, Shimizu T. Tojo S, et al. Among authors: tsutsumi a. Nat Commun. 2020 Oct 15;11(1):5204. doi: 10.1038/s41467-020-19025-z. Nat Commun. 2020. PMID: 33060576 Free PMC article.
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion.
Matoba K, Kotani T, Tsutsumi A, Tsuji T, Mori T, Noshiro D, Sugita Y, Nomura N, Iwata S, Ohsumi Y, Fujimoto T, Nakatogawa H, Kikkawa M, Noda NN. Matoba K, et al. Among authors: tsutsumi a. Nat Struct Mol Biol. 2020 Dec;27(12):1185-1193. doi: 10.1038/s41594-020-00518-w. Epub 2020 Oct 26. Nat Struct Mol Biol. 2020. PMID: 33106658
Mitochondrial sorting and assembly machinery operates by β-barrel switching.
Takeda H, Tsutsumi A, Nishizawa T, Lindau C, Busto JV, Wenz LS, Ellenrieder L, Imai K, Straub SP, Mossmann W, Qiu J, Yamamori Y, Tomii K, Suzuki J, Murata T, Ogasawara S, Nureki O, Becker T, Pfanner N, Wiedemann N, Kikkawa M, Endo T. Takeda H, et al. Among authors: tsutsumi a. Nature. 2021 Feb;590(7844):163-169. doi: 10.1038/s41586-020-03113-7. Epub 2021 Jan 6. Nature. 2021. PMID: 33408415
564 results