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Page 1
Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells.
Di Stefano B, Ueda M, Sabri S, Brumbaugh J, Huebner AJ, Sahakyan A, Clement K, Clowers KJ, Erickson AR, Shioda K, Gygi SP, Gu H, Shioda T, Meissner A, Takashima Y, Plath K, Hochedlinger K. Di Stefano B, et al. Nat Methods. 2018 Sep;15(9):732-740. doi: 10.1038/s41592-018-0104-1. Epub 2018 Aug 20. Nat Methods. 2018. PMID: 30127506 Free PMC article.
Cell reprogramming: Brain versus brawn.
Di Stefano B, Hochedlinger K. Di Stefano B, et al. Nature. 2016 Jun 16;534(7607):332-3. doi: 10.1038/nature18444. Epub 2016 Jun 8. Nature. 2016. PMID: 27281201 No abstract available.
Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells.
Choi J, Huebner AJ, Clement K, Walsh RM, Savol A, Lin K, Gu H, Di Stefano B, Brumbaugh J, Kim SY, Sharif J, Rose CM, Mohammad A, Odajima J, Charron J, Shioda T, Gnirke A, Gygi S, Koseki H, Sadreyev RI, Xiao A, Meissner A, Hochedlinger K. Choi J, et al. Among authors: di stefano b. Nature. 2017 Aug 10;548(7666):219-223. doi: 10.1038/nature23274. Epub 2017 Jul 26. Nature. 2017. PMID: 28746311 Free PMC article.
Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling.
Brumbaugh J, Di Stefano B, Wang X, Borkent M, Forouzmand E, Clowers KJ, Ji F, Schwarz BA, Kalocsay M, Elledge SJ, Chen Y, Sadreyev RI, Gygi SP, Hu G, Shi Y, Hochedlinger K. Brumbaugh J, et al. Among authors: di stefano b. Cell. 2018 Jan 11;172(1-2):106-120.e21. doi: 10.1016/j.cell.2017.11.023. Epub 2017 Dec 14. Cell. 2018. PMID: 29249356 Free PMC article.
Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling.
Brumbaugh J, Di Stefano B, Wang X, Borkent M, Forouzmand E, Clowers KJ, Ji F, Schwarz BA, Kalocsay M, Elledge SJ, Chen Y, Sadreyev RI, Gygi SP, Hu G, Shi Y, Hochedlinger K. Brumbaugh J, et al. Among authors: di stefano b. Cell. 2018 Jan 25;172(3):629-631. doi: 10.1016/j.cell.2017.12.035. Cell. 2018. PMID: 29373832 Free PMC article. No abstract available.
Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors.
Bar-Nur O, Gerli MFM, Di Stefano B, Almada AE, Galvin A, Coffey A, Huebner AJ, Feige P, Verheul C, Cheung P, Payzin-Dogru D, Paisant S, Anselmo A, Sadreyev RI, Ott HC, Tajbakhsh S, Rudnicki MA, Wagers AJ, Hochedlinger K. Bar-Nur O, et al. Among authors: di stefano b. Stem Cell Reports. 2018 May 8;10(5):1505-1521. doi: 10.1016/j.stemcr.2018.04.009. Stem Cell Reports. 2018. PMID: 29742392 Free PMC article.
Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.
Sardina JL, Collombet S, Tian TV, Gómez A, Di Stefano B, Berenguer C, Brumbaugh J, Stadhouders R, Segura-Morales C, Gut M, Gut IG, Heath S, Aranda S, Di Croce L, Hochedlinger K, Thieffry D, Graf T. Sardina JL, et al. Among authors: di croce l, di stefano b. Cell Stem Cell. 2018 Nov 1;23(5):727-741.e9. doi: 10.1016/j.stem.2018.08.016. Epub 2018 Sep 13. Cell Stem Cell. 2018. PMID: 30220521 Free article.
Novel Roles for SUMOylation in Cellular Plasticity.
Di Stefano B, Hochedlinger K. Di Stefano B, et al. Trends Cell Biol. 2018 Dec;28(12):971-973. doi: 10.1016/j.tcb.2018.10.001. Epub 2018 Oct 26. Trends Cell Biol. 2018. PMID: 30463679 Free PMC article.
The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis.
Di Stefano B, Luo EC, Haggerty C, Aigner S, Charlton J, Brumbaugh J, Ji F, Rabano Jiménez I, Clowers KJ, Huebner AJ, Clement K, Lipchina I, de Kort MAC, Anselmo A, Pulice J, Gerli MFM, Gu H, Gygi SP, Sadreyev RI, Meissner A, Yeo GW, Hochedlinger K. Di Stefano B, et al. Cell Stem Cell. 2019 Nov 7;25(5):622-638.e13. doi: 10.1016/j.stem.2019.08.018. Epub 2019 Oct 3. Cell Stem Cell. 2019. PMID: 31588046 Free PMC article.
Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo.
Brumbaugh J, Kim IS, Ji F, Huebner AJ, Di Stefano B, Schwarz BA, Charlton J, Coffey A, Choi J, Walsh RM, Schindler JW, Anselmo A, Meissner A, Sadreyev RI, Bernstein BE, Hock H, Hochedlinger K. Brumbaugh J, et al. Among authors: di stefano b. Nat Cell Biol. 2019 Nov;21(11):1449-1461. doi: 10.1038/s41556-019-0403-5. Epub 2019 Oct 28. Nat Cell Biol. 2019. PMID: 31659274 Free PMC article.
68 results