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Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells.
Jin J, Tarrant RD, Bolam EJ, Angell-Manning P, Soegaard M, Pattinson DJ, Dulal P, Silk SE, Marshall JM, Dabbs RA, Nugent FL, Barrett JR, Hjerrild KA, Poulsen L, Jørgensen T, Brenner T, Baleanu IN, Parracho HM, Tahiri-Alaoui A, Whale G, Moyle S, Payne RO, Minassian AM, Higgins MK, Detmers FJ, Lawrie AM, Douglas AD, Smith R, de Jongh WA, Berrie E, Ashfield R, Draper SJ. Jin J, et al. Among authors: angell manning p. NPJ Vaccines. 2018 Aug 17;3:32. doi: 10.1038/s41541-018-0071-7. eCollection 2018. NPJ Vaccines. 2018. PMID: 30131879 Free PMC article.
Production of a high purity, C-tagged hepatitis B surface antigen fusion protein VLP vaccine for malaria expressed in Pichia pastoris under cGMP conditions.
Mukhopadhyay E, Brod F, Angell-Manning P, Green N, Tarrant RD, Detmers FJ, Bolam EJ, Baleanu IN, Hobson M, Whale G, Morris SJ, Ashfield R, Gilbert SC, Jin J, Draper SJ, Moyle SP, Berrie EL, Hill AVS. Mukhopadhyay E, et al. Among authors: angell manning p. Biotechnol Bioeng. 2022 Oct;119(10):2784-2793. doi: 10.1002/bit.28181. Epub 2022 Jul 22. Biotechnol Bioeng. 2022. PMID: 35822551 Free PMC article.
R21 in Matrix-M adjuvant in UK malaria-naive adult men and non-pregnant women aged 18-45 years: an open-label, partially blinded, phase 1-2a controlled human malaria infection study.
Venkatraman N, Silman D, Bellamy D, Stockdale L, Bowyer G, Edwards NJ, Griffiths O, Lopez FR, Powlson J, Mair C, Folegatti PM, Datoo MS, Morter R, Minassian AM, Poulton I, Collins KA, Brod F, Angell-Manning P, Berrie E, Brendish N, Glenn G, Fries L, Baum J, Blagborough AM, Roberts R, Lawrie AM, Angus B, Lewis DJM, Faust SN, Ewer KJ, Hill AVS. Venkatraman N, et al. Among authors: angell manning p. Lancet Microbe. 2025 Jan 9:100867. doi: 10.1016/S2666-5247(24)00083-1. Online ahead of print. Lancet Microbe. 2025. PMID: 39805301 Free article.
Simian adenovirus vector production for early-phase clinical trials: A simple method applicable to multiple serotypes and using entirely disposable product-contact components.
Fedosyuk S, Merritt T, Peralta-Alvarez MP, Morris SJ, Lam A, Laroudie N, Kangokar A, Wright D, Warimwe GM, Angell-Manning P, Ritchie AJ, Gilbert SC, Xenopoulos A, Boumlic A, Douglas AD. Fedosyuk S, et al. Among authors: angell manning p. Vaccine. 2019 Nov 8;37(47):6951-6961. doi: 10.1016/j.vaccine.2019.04.056. Epub 2019 Apr 30. Vaccine. 2019. PMID: 31047679 Free PMC article.