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Open study with (-)-OSU6162 in multiple sclerosis-related fatigue.
Haghighi S, Forsmark S, Carlsson A, Nilsson MKL, Carlsson ML, Schuit RC, Gottfries CG. Haghighi S, et al. Among authors: schuit rc. Acta Neurol Scand. 2018 Dec;138(6):482-489. doi: 10.1111/ane.13007. Epub 2018 Aug 22. Acta Neurol Scand. 2018. PMID: 30132786 Clinical Trial.
Validation of simplified uptake measures against dynamic Patlak Ki for quantification of lesional 89Zr-Immuno-PET antibody uptake.
Wijngaarden JE, Huisman MC, Jauw YWS, van Dongen GAMS, Greuter HNJM, Schuit RC, Cleveland M, Gootjes EC, Vugts DJ, Menke-van der Houven van Oordt CW, Boellaard R. Wijngaarden JE, et al. Among authors: schuit rc. Eur J Nucl Med Mol Imaging. 2023 Jun;50(7):1897-1905. doi: 10.1007/s00259-023-06151-1. Epub 2023 Feb 23. Eur J Nucl Med Mol Imaging. 2023. PMID: 36820891 Free PMC article.
Synthesis and preclinical evaluation of two osimertinib isotopologues labeled with carbon-11 as PET tracers targeting the tyrosine kinase domain of the epidermal growth factor receptor.
Högnäsbacka A, Poot AJ, Kooijman E, Schuit RC, Schreurs M, Verlaan M, van den Hoek J, Heideman DAM, Beaino W, van Dongen GAMS, Vugts DJ, Windhorst AD. Högnäsbacka A, et al. Among authors: schuit rc. Nucl Med Biol. 2023 May-Jun;120-121:108349. doi: 10.1016/j.nucmedbio.2023.108349. Epub 2023 May 4. Nucl Med Biol. 2023. PMID: 37209556 Free article.
The dopamine stabilizer (-)-OSU6162 occupies a subpopulation of striatal dopamine D2/D3 receptors: an [(11)C]raclopride PET study in healthy human subjects.
Tolboom N, Berendse HW, Leysen JE, Yaqub M, van Berckel BN, Schuit RC, Ponsen MM, Bakker E, Hoetjes NJ, Windhorst AD, Carlsson ML, Lammertsma AA, Carlsson A. Tolboom N, et al. Among authors: schuit rc. Neuropsychopharmacology. 2015 Jan;40(2):472-9. doi: 10.1038/npp.2014.195. Epub 2014 Aug 5. Neuropsychopharmacology. 2015. PMID: 25248987 Free PMC article.
In vivo assessment of neuroinflammation in progressive multiple sclerosis: a proof of concept study with [18F]DPA714 PET.
Hagens MHJ, Golla SV, Wijburg MT, Yaqub M, Heijtel D, Steenwijk MD, Schober P, Brevé JJP, Schuit RC, Reekie TA, Kassiou M, van Dam AM, Windhorst AD, Killestein J, Barkhof F, van Berckel BNM, Lammertsma AA. Hagens MHJ, et al. Among authors: schuit rc. J Neuroinflammation. 2018 Nov 13;15(1):314. doi: 10.1186/s12974-018-1352-9. J Neuroinflammation. 2018. PMID: 30424780 Free PMC article.
The P2X7 receptor tracer [11C]SMW139 as an in vivo marker of neuroinflammation in multiple sclerosis: a first-in man study.
Hagens MHJ, Golla SSV, Janssen B, Vugts DJ, Beaino W, Windhorst AD, O'Brien-Brown J, Kassiou M, Schuit RC, Schwarte LA, de Vries HE, Killestein J, Barkhof F, van Berckel BNM, Lammertsma AA. Hagens MHJ, et al. Among authors: schuit rc. Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):379-389. doi: 10.1007/s00259-019-04550-x. Epub 2019 Nov 8. Eur J Nucl Med Mol Imaging. 2020. PMID: 31705174 Free PMC article.
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