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Eomes controls the development of Th17-derived (non-classic) Th1 cells during chronic inflammation.
Mazzoni A, Maggi L, Siracusa F, Ramazzotti M, Rossi MC, Santarlasci V, Montaini G, Capone M, Rossettini B, De Palma R, Kruglov A, Chang HD, Cimaz R, Maggi E, Romagnani S, Liotta F, Cosmi L, Annunziato F. Mazzoni A, et al. Among authors: capone m. Eur J Immunol. 2019 Jan;49(1):79-95. doi: 10.1002/eji.201847677. Epub 2018 Nov 22. Eur J Immunol. 2019. PMID: 30144030 Free article.
Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.
Cosmi L, De Palma R, Santarlasci V, Maggi L, Capone M, Frosali F, Rodolico G, Querci V, Abbate G, Angeli R, Berrino L, Fambrini M, Caproni M, Tonelli F, Lazzeri E, Parronchi P, Liotta F, Maggi E, Romagnani S, Annunziato F. Cosmi L, et al. Among authors: capone m. J Exp Med. 2008 Aug 4;205(8):1903-16. doi: 10.1084/jem.20080397. Epub 2008 Jul 28. J Exp Med. 2008. PMID: 18663128 Free PMC article.
CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC.
Maggi L, Santarlasci V, Capone M, Peired A, Frosali F, Crome SQ, Querci V, Fambrini M, Liotta F, Levings MK, Maggi E, Cosmi L, Romagnani S, Annunziato F. Maggi L, et al. Among authors: capone m. Eur J Immunol. 2010 Aug;40(8):2174-81. doi: 10.1002/eji.200940257. Eur J Immunol. 2010. PMID: 20486123 Free article.
Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis.
Cosmi L, Cimaz R, Maggi L, Santarlasci V, Capone M, Borriello F, Frosali F, Querci V, Simonini G, Barra G, Piccinni MP, Liotta F, De Palma R, Maggi E, Romagnani S, Annunziato F. Cosmi L, et al. Among authors: capone m. Arthritis Rheum. 2011 Aug;63(8):2504-15. doi: 10.1002/art.30332. Arthritis Rheum. 2011. PMID: 21381000 Free article.
Rarity of human T helper 17 cells is due to retinoic acid orphan receptor-dependent mechanisms that limit their expansion.
Santarlasci V, Maggi L, Capone M, Querci V, Beltrame L, Cavalieri D, D'Aiuto E, Cimaz R, Nebbioso A, Liotta F, De Palma R, Maggi E, Cosmi L, Romagnani S, Annunziato F. Santarlasci V, et al. Among authors: capone m. Immunity. 2012 Feb 24;36(2):201-14. doi: 10.1016/j.immuni.2011.12.013. Epub 2012 Feb 9. Immunity. 2012. PMID: 22326581 Free article.
Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells.
Maggi L, Santarlasci V, Capone M, Rossi MC, Querci V, Mazzoni A, Cimaz R, De Palma R, Liotta F, Maggi E, Romagnani S, Cosmi L, Annunziato F. Maggi L, et al. Among authors: capone m. Eur J Immunol. 2012 Dec;42(12):3180-8. doi: 10.1002/eji.201242648. Epub 2012 Oct 25. Eur J Immunol. 2012. PMID: 22965818 Free article. Clinical Trial.
IL-4-induced gene 1 maintains high Tob1 expression that contributes to TCR unresponsiveness in human T helper 17 cells.
Santarlasci V, Maggi L, Mazzoni A, Capone M, Querci V, Rossi MC, Beltrame L, Cavalieri D, De Palma R, Liotta F, Cosmi L, Maggi E, Romagnani S, Annunziato F. Santarlasci V, et al. Among authors: capone m. Eur J Immunol. 2014 Mar;44(3):654-61. doi: 10.1002/eji.201344047. Epub 2013 Dec 27. Eur J Immunol. 2014. PMID: 24307243 Free article.
348 results